The Historical Development of Animal Toxicity Testing [PDF]
, 2012 This paper traces the historical development of animal toxicity testing, from its ancient origins through the period of standardization following World War II.
Gertler, N.
core
Determination of Tramadol in human plasma by HPLC with fluorescence detection [PDF]
, 2016 Tramadol is a centrally acting analgesic, atypical opioid, and although it is generally considered as a medicinal drug with a low potential for dependence, there is growing evidence of tramadol abuse in some countries.
Abdul Jalil Ebrahim, Zainab +4 more
core +2 more sources
Evaluation of polycyclic aromatic hydrocarbons using analytical methods, toxicology, and risk assessment research: seafood safety after a petroleum spill as an example. [PDF]
, 2014 BackgroundPolycyclic aromatic hydrocarbons (PAHs) are abundant and widespread environmental chemicals. They are produced naturally and through man-made processes, and they are common in organic media, including petroleum.
Ansari, Shakeel +15 more
core +1 more source
Failure of Optimal Design Theory? A Case Study in Toxicology Using Sequential Robust Optimal Design Framework [PDF]
arXivThis paper presents a quasi-sequential optimal design framework for toxicology experiments, specifically applied to sea urchin embryos. The authors propose a novel approach combining robust optimal design with adaptive, stage-based testing to improve efficiency in toxicological studies, particularly where traditional uniform designs fall short.
arxiv
Efficacy of a two bag acetylcysteine regimen to treat paracetamol overdose (2NAC study)
EClinicalMedicine, 2020 Background: Previous studies of paracetamol overdose treatment show that a 2-bag, 20-h intravenous (IV) acetylcysteine regimen decreased the incidence of non-allergic anaphylactic reactions compared to the 3-bag, 21 h IV regimen, but have not examined ...
Anselm Wong +10 more
doaj
Data Poisoning against Differentially-Private Learners: Attacks and Defenses [PDF]
arXiv, 2019 Data poisoning attacks aim to manipulate the model produced by a learning algorithm by adversarially modifying the training set. We consider differential privacy as a defensive measure against this type of attack. We show that such learners are resistant to data poisoning attacks when the adversary is only able to poison a small number of items ...
arxiv
Advances in the Use of Mass Spectral Libraries for Forensic Toxicology [PDF]
, 2017 Gas chromatography in combination with mass spectrometry (GC-MS) plays an important role in the field of analytical toxicology. The identification of unknown compounds is very frequently undertaken with GC-MS and utilizing mass spectral libraries ...
Aebi, Beat, Bernhard, Werner
core
Nursing, 2019 ABSTRACT: Toxicology is an interesting and specialized branch of medicine. This article examines the parallels between nursing and working as a specialist in poison information, offering a different career path for eligible nurses.
openaire +4 more sources
A Systematic Review of Poisoning Attacks Against Large Language Models [PDF]
arXivWith the widespread availability of pretrained Large Language Models (LLMs) and their training datasets, concerns about the security risks associated with their usage has increased significantly. One of these security risks is the threat of LLM poisoning attacks where an attacker modifies some part of the LLM training process to cause the LLM to behave
arxiv
Some results for poisoning in a catalytic model [PDF]
arXiv, 2006 We obtain new results concerning poisoning/nonpoisoning in a catalytic model which has previously been introduced and studied. We show that poisoning can occur even when the arrival rate of one gas is smaller than the sum of the arrival rates of the other gases, and that poisoning does not occur when all gases have equal arrival rates.
arxiv