Results 111 to 120 of about 398,369 (366)

Inconsistent Transcriptomic Responses to Hexabromocyclododecane in Japanese Quail: A Comparative Analysis of Results From Four Different Study Designs

open access: yesEnvironmental Toxicology and Chemistry, EarlyView.
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers   +10 more
wiley   +1 more source

Metabolomics Assessment of the Mitigation of Lead‐Induced Inflammation in Adult Zebrafish (Danio rerio) by a Fermented Soybean Extract

open access: yesFood Safety and Health, EarlyView.
Fermented soybean extract (FSE) at 50 mg/L has the potential to mitigate lead (Pb) toxicity (5 mg/L) observed in the zebrafish model. This study offers insights into food intervention in toxicology. ABSTRACT This study investigated the potential of fermented soybean extract (FSE) as an alternative therapy for lead (Pb) toxicity, without chelation side ...
Siok‐Geok Chong, Intan Safinar Ismail
wiley   +1 more source

Impact of Endocrine‐Disrupting Chemicals (EDCs) Used in the Food Industry on Endocrine Abnormalities

open access: yesFood Safety and Health, EarlyView.
This review was conducted to examine the relationship between hormone disruption and other endocrine abnormalities in the context of the constant consumption of genetically modified foods and overexposure to chemicals used directly and indirectly in the agrifood industry.
Perla D. Serrano‐López   +3 more
wiley   +1 more source

Dietary topoisomerase II-poisons [PDF]

open access: yes, 2002
DNA topoisomerases are nuclear enzymes inducing transient breaks in the DNA allowing DNA strands or double helices to pass through each other. The clinically used DNA topoisomerase II-poison etoposide is known to induce DNA double strand breaks leading ...
Bolt, Hermann M.   +7 more
core  

Trace Metal Contamination and Health Risk Assessment in Traditional Egyptian Soft Cheeses: A Food Safety Perspective

open access: yesFood Safety and Health, EarlyView.
This study evaluates trace metal concentrations in traditional Egyptian soft cheeses and assesses associated health risks using chemometric and toxicological approaches. Findings confirm the safety of these cheeses, with all risk indices within acceptable limits, supporting the need for continued monitoring to ensure food quality and consumer ...
Hani S. Abdelmontaleb   +3 more
wiley   +1 more source

Assessing the Acute and Chronic Effects of Palladium on Daphnia magna and the Influence of Natural Organic Matter

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT In recent decades, rising industrial demand for palladium (Pd), driven by its unique properties and affordability compared to other noble metals, has increased its environmental release into aquatic systems. This highlights the need to assess its effects on organisms, given the lack of standardized toxicity studies and regulations for this ...
Rania Boukhari   +4 more
wiley   +1 more source

Efficacy of a two bag acetylcysteine regimen to treat paracetamol overdose (2NAC study)

open access: yesEClinicalMedicine, 2020
Background: Previous studies of paracetamol overdose treatment show that a 2-bag, 20-h intravenous (IV) acetylcysteine regimen decreased the incidence of non-allergic anaphylactic reactions compared to the 3-bag, 21 h IV regimen, but have not examined ...
Anselm Wong   +10 more
doaj  

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