Results 61 to 70 of about 397,117 (262)
Similarity of multiple dose-response curves in interlaboratory studies in regulatory toxicology [PDF]
arXiv, 2020 To claim similarity of multiple dose-response curves in interlaboratory studies in regulatory toxicology is a relevant issue during the assay validation process. Here we demonstrated the use of dose-by-laboratory interaction contrasts, particularly Williams-type by total mean contrasts.
arxiv
Frontiers in Toxicology, 2022 Biomonitoring of workers is an approach of evaluating workers’ exposure to chemicals and particulate matter by measuring biomarkers of parent chemicals, their metabolites, and reaction products in workers’ biospecimens.
Boowook Kim +14 more
doaj +1 more source
Statistical evaluation of in-vivo bioassays in regulatory toxicology considering males and females [PDF]
arXiv, 2020 The separate evaluation for males and females is the recent standard in in-vivo toxicology for dose or treatment effects using Dunnett tests. The alternative pre-test for sex-by-treatment interaction is problematic. Here a joint test is proposed considering the two sex-specific and the pooled Dunnett-type comparisons.
arxiv
DARU Journal of Pharmaceutical Sciences, 2017 BackgroundSuicide ranks among the top ten causes of death in all age groups all over the world. There are many methods for committing suicide including self-poisoning, firearm and hanging.
Roya Kordrostami +4 more
semanticscholar +1 more source
Ivabradine poisoning: a retrospective observational case series
Toxicology CommunicationsIntroduction Ivabradine is an anti-arrhythmic drug that targets the cardiac pacemaker funny current (If). It is used in the management of patients with uncontrolled angina, heart failure and postural orthostatic tachycardia syndrome.
Muhammad Nursuhairi Bin Sumarni +4 more
doaj +1 more source
Chemical Atherogenesis: Role of Endogenous and Exogenous Poisons in Disease Development
Toxics, 2014 Chemical atherogenesis is an emerging field that describes how environmental pollutants and endogenous toxins perturb critical pathways that regulate lipid metabolism and inflammation, thus injuring cells found within the vessel wall.
Matthew K. Ross +2 more
doaj +1 more source
Microplastics and Their Impact on Reproduction—Can we Learn From the C. elegans Model?
Frontiers in Toxicology, 2022 Biologically active environmental pollutants have significant impact on ecosystems, wildlife, and human health. Microplastic (MP) and nanoplastic (NP) particles are pollutants that are present in the terrestrial and aquatic ecosystems at virtually every ...
Elysia Jewett +4 more
doaj +1 more source
Closing Evidence Gaps on the Prevalence and Harms of New Psychoactive Substances in Scotland [PDF]
, 2015 This paper considers the state of knowledge on New Psychoactive Substances (NPS) in Scotland, with a focus on prevalence and harms and puts forward proposals which may assist in closing existing evidence ...
Gillies, Allan
core
Toxicology Reports, 2023 There is limited literature on managing chronic lead exposure from non-removable sources such as lead fragments. In this case report, we present the complexities and clinical considerations involved in treating an elderly patient who sustained a ...
Ilaria Costantini +9 more
doaj
Clinical Review: Emergency management of acute poisoning
African Journal of Emergency Medicine, 2011 Acutely poisoned patients are commonly encountered in Emergency Centres. Acute poisoning (accidental or intentional) requires accurate assessment and prompt therapy.
D.J. van Hoving +2 more
doaj +1 more source