Results 251 to 260 of about 839,197 (349)

13-Month Follow Up of Acclimation of Cynomolgus Macaques (Macaca fascicularis) on Haematology, Serum Biochemistry, and Body Weight Changes. [PDF]

J Med Primatol
Rho J, Son HY, Kim SH, Suh HN.
europepmc   +1 more source

Affinity‐Based Protein Profiling Revealed that HIGD1A is a Direct Target Protein of Aristolochic Acids

Advanced Science, EarlyView.
Using an affinity‐based probe, this study reveals that aristolochic acid directly binds to HIGD1A with high affinity in the kidney. This binding disrupts the HIGD1A‐TFAM interaction, which in turn triggers TFAM degradation, cytosolic mitochondrial DNA release, and the activation of inflammatory pathways. Abstract Exposure to aristolochic acids (AA) via
Yin Gong, Shanshan Zhang, Anying Wei, Xiang Ji, Xiaodan Chong, Jinfeng Cen, Xuan Zhao, Zimeng Luo, Zhipeng Pei, Guanchao Mao, Xinkang Zhang, Mingxue Sun, Zhiguo Sun, Zifei Yin, Zhengrong Zou, Wen‐Qi Meng   +15 more
wiley   +1 more source

Exploring the mechanism of methyl parathion and its degradation product on depression through network toxicology and molecular docking. [PDF]

Sci Rep
Cao M, Fan BB, Xu LS, Xu J, Zhang YH.
europepmc   +1 more source

How Operant Conditioning Can Contribute to Behavioral Toxicology

, 1978
Victor G. Laties
openalex   +1 more source

Overcoming EGFR‐Mediated Dendritic Cell Dysfunction to Enhance Anti‐tumor Immunity in EGFR‐Mutant NSCLC by Precisely Targeting CD73 With pH‐responsive Nanocarriers

Advanced Science, EarlyView.
EGFR mutations drive ERK/c‐Jun–mediated transcriptional activation of CD73, elevating adenosine levels and fostering an immunosuppressive TME by impairing DC maturation and CD8⁺ T cell priming. The pH‐responsive nanodrug F127ZIF‐8AB680 selectively inhibits CD73, normalizes adenosine metabolism, and re‐establishes effective anti‐tumor immunity ...
Xiaoling Shang, Xudong Geng, Zixu Wang, Shumin Yuan, Shanshan Ding, Ni Liu, Xinchun Ma, Xuan Sun, Huimin Wang, Ying Sun, Xun Qu, Guangwen Ren, Yong Qiang Li, Xiuwen Wang, Yanguo Liu   +14 more
wiley   +1 more source

IND-Enabling Preclinical Studies of [¹¹C]COU, a Trapped Metabolite PET Radiotracer for Monoamine Oxidase-B. [PDF]

Med Chem Res
Frazier M, Kaur T, Stauff J, Winton WP, Henderson BD, Dumond AS, Shao X, Raffel DM, Frey KA, Kilbourn MR, Brooks AF, Scott PJH.   +11 more
europepmc   +1 more source

The clinical toxicology of caffeine: A review and case study

Toxicology Reports, 2018
C. Willson
semanticscholar   +1 more source

Emerging Nanozyme Strategies for Precision Breast Cancer Treatment

Advanced Science, EarlyView.
Different types of nanozymes‐mediated chemotherapy, photothermal therapy, immunotherapy, and multiple combined therapies for the effective treatment of breast cancer. Abstract Breast cancer, the most common malignant tumor among women worldwide, poses a significant challenge to public health due to its high incidence and mortality rates.
Jian Zang, Zhaozhou Ren, Haibo Wang, Xing Yang, Yang Song, Jun Liao, Xiaoying Li   +6 more
wiley   +1 more source

Antidotes in Depth 2010. Clinical Toxicology, Substances of Abuse and Chemical Emergencies

, 2011
The Editors
openalex   +2 more sources

Physical, Proximate and Toxicological Properties of Andrographis Paniculata Herbal Powder Beverage Mix

, 2020
Etti CJ
openalex   +1 more source