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Toxicological screening

Regulatory Toxicology and Pharmacology, 1984
Well-defined dose- and time-related toxic effects of chemicals can often be detected using simple tests with small numbers of animals. The strategies for the establishment of toxicological screening tests are discussed. The most important steps are the definition of the targets, the selection of the methods, and the setting of the test criteria ...
G, Zbinden, J, Elsner, U A, Boelsterli
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A Toxicology Databank—The Registry of Human Toxicology

Human Toxicology, 1983
1 The Registry of Human Toxicology is a databank designed to assist in the interpretation of results obtained from the analysis of human body organs for toxic substances. 2 The present Registry contains over 16,000 analyses from 4309 cases giving details of 282 compounds and 360 preparations.
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The Toxicology of Mycotoxins

CRC Critical Reviews in Toxicology, 1985
Mycotoxin problems are one of great concern to health scientists. Toxic fungal metabolites such as aflatoxins, trichothecenes, zearalenone and others are contaminated in our environments and induce various diseases. In this manuscript, the author will summarize the recent advances on toxicology of mycotoxins in special references to toxicological ...
Yoshio Ueno, Dennis P. H. Hsieh
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Biomarkers in toxicology

Toxicology, 1998
The use of biomarkers in toxicology is becoming increasingly important. This article briefly reviews some of the aspects in an attempt to give an overall view of the field. Some of the new developments, particularly in relation to biomarkers of exposure and response, are mentioned.
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Postmortem toxicology

Forensic Science, Medicine, and Pathology, 2010
Results from toxicological analyses in death investigations are used to determine whether foreign substances were a cause of death, whether they contributed to death, or whether they caused impairment. Drug concentrations are likely to change during pre-terminal stages due to altered pharmacokinetics, to treatment during resuscitation or in the ...
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The Toxicology of Chlorine

Environmental Research, 2001
Chlorine is a reactive gas used by humanity for over two centuries. Exposure to chlorine has occurred in a number of situations, including as a chemical warfare agent, in industrial and domestic exposures, and as a result of accidents and spills. The toxicology of chlorine is related almost entirely to effects in the respiratory system.
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Toxicology of Aldicarb

1988
Aldicarb (2-methyl-2[methylthio]propionaldehyde 0-[methyl carbamoyl]-oxime; TEMIK®, Rhone-Poilenc’s registered trademark) effectively controls a wide variety of insects, mites, and nematodes and is used worldwide on more than 40 economically important crops.
R L, Baron, T L, Merriam
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Toxicology of Cimetidine

Human Toxicology, 1985
1 Cimetidine has been shown to have low acute toxicity in dogs and rodents. Repeated-dose studies of up to 24 months' duration in rodents at doses up to 950 mg day kg -1 showed few adverse effects.
R W, Brimblecombe   +2 more
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Avian Toxicology

Veterinary Clinics of North America: Small Animal Practice, 1991
Owing to the unique physiology of birds, most toxicities are life-threatening and require prompt, well-informed action. It is often hard to ascertain which specific toxin or the amount of toxin to which the bird has been exposed. Therefore, the most important action is to treat the bird, not the poison.
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The Toxicology of Perfluorooctanoate

Critical Reviews in Toxicology, 2004
PFOA is a peroxisome proliferator (PPAR agonist) and exerts morphological and biochemical effects characteristic of PPAR agonists. These effects include increased beta-oxidation of fatty acids, increases in several cytochrome P-450 (CYP450)-mediated reactions, and inhibition of the secretion of very low-density lipoproteins and cholesterol from the ...
Gerald L, Kennedy   +8 more
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