Results 341 to 350 of about 820,187 (404)

ROS‐induced modifications of fibrin clots connect immune responses to atherothrombosis in systemic lupus erythematosus

Arthritis &Rheumatology, Accepted Article.
Objective Cardiovascular events are major determinants of morbidity and mortality in systemic lupus erythematosus (SLE), particularly in patients with renal involvement. While oxidative stress has been implicated in driving vascular and renal damage in SLE, the specific mechanisms remain unclear.
Matteo Becatti, Giacomo Emmi, Alessandra Bettiol, Amanda Mannucci, Flavia Rita Argento, Eleonora Fini, Serena Borghi, Francesca Nencini, Maria Nicastro, Irene Mattioli, Elena Silvestri, Augusto Vaglio, Domenico Prisco, Claudia Fiorillo   +13 more
wiley   +1 more source

The Potential Mechanisms of Ochratoxin A in Prostate Cancer Development: An Integrated Study Combining Network Toxicology, Machine Learning, and Molecular Docking. [PDF]

Toxins (Basel)
Cai H, Shen D, Hu X, Yin H, Yan Z.
europepmc   +1 more source

The Tower of Babel in science communication on social media: An analysis of linguistic diversity in Twitter mentions of scientific publications

Journal of the Association for Information Science and Technology, EarlyView.
Abstract To unravel the linguistic dynamics of science communication on social media, this study presents a large‐scale, cross‐disciplinary analysis of language use in over 21 million Twitter mentions of 6.7 million scientific publications. While English dominates—accounting for 90.8% of all mentions and serving as a bridging language for the ...
Yanqing Zhang, Zhichao Fang
wiley   +1 more source

Correction: Urolithin a Improves Motor Dysfunction Induced by Copper Exposure in SOD1^G93A Transgenic Mice Via Activation of Mitophagy. [PDF]

Mol Neurobiol
Zhang H, Gao C, Yang D, Nie L, He K, Chen C, Li S, Huang G, Zhou L, Huang X, Wu D, Liu J, Huang Z, Wang J, Li W, Zhang Z, Yang X, Zou L.   +17 more
europepmc   +1 more source

The fate of thiopurine metabolites after switching to low‐dose thiopurine with allopurinol or thioguanine in IBD patients: A retrospective analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Shunting (hypermethylating) thiopurine metabolism, characterized by excessive 6‐MMPR production and (sub)therapeutic 6‐TGN levels, poses a significant challenge in the treatment of inflammatory bowel disease (IBD). This study evaluates the metabolic outcomes of switching to low‐dose thiopurine with allopurinol (LDTA) or thioguanine (TG) in IBD ...
Ahmed B. Bayoumy, Hedwig M. A. D'Agnolo, Nanne K. H. de Boer, Chris J. J. Mulder, Luc J. J. Derijks   +4 more
wiley   +1 more source

Restraint-Based ECG and Arterial Pressure Assessment Do Not Reliably Detect Drug Induced QTc Prolongation and Hypotension: Evidence From Case Studies. [PDF]

Clin Transl Sci
Henderson KA, Ether N, Vargas HM.
europepmc   +1 more source

The use of international classification of diseases codes to identify hospital admissions linked with adverse drug events: Validation study

British Journal of Clinical Pharmacology, EarlyView.
Aims Several methods exist to identify hospital admissions related to adverse drug events (ADEs). Clinical adjudication by healthcare professionals is the gold standard but is labour‐intensive. Spontaneous reporting and routinely collected healthcare data using a set of International Classification of Diseases (ICD) codes often underestimate the ...
Zuzana Juhásová, Fatma Karapinar‐Çarkit, Daniala L. Weir   +2 more
wiley   +1 more source

Biochemical Identification and Clinical Description of Medetomidine Exposure in People Who Use Fentanyl in Philadelphia, PA. [PDF]

Int J Mol Sci
Durney P, Kahoud JL, Warrick-Stone T, Montesi M, Carter M, Butt S, Mencia AM, Omoregie L, Shah M, Bloomfield M, Tomasko N, Jaffe R, Herens A, Korn WR, Alexander K, Stickle D, Goodstein D, Weinstein LC, London KS.   +18 more
europepmc   +1 more source

Contribution of Addictovigilance data to assess adverse‐events linked to psychoactive substances in children and adolescents

British Journal of Clinical Pharmacology, EarlyView.
Aims We sought to characterize adverse events and deaths associated with the use of psychoactive substances in children and adolescents. Methods Two French Addictovigilance databases were analysed: spontaneous reports and deaths over the period 2016–2021, in subjects aged 10–<18 years. An unsupervised classification was implemented on consumption data (
Hélène Peyrière, Anne Batisse, Nathalie Fouilhé Sam‐Laï, Amélie Daveluy, Christine Fournier‐Choma, Sylvie Deheul, Cécile Chevalier, Clémence Lacroix, Valérie Gibaja, Aurélie Aquizerate, Stéphanie Pain, Emilie Jouanjus, Marie‐Christine Picot, Erika Nogue   +13 more
wiley   +1 more source

Prevalence and predictors of substance use as a factor in suicide in the USA, 2015-2020: a repeated cross-sectional analysis. [PDF]

BMJ Public Health
Phillips JA.
europepmc   +1 more source