Retrospective Evaluation of the Prevalence and Prognosis of Hypochloremia in Dogs and Cats. [PDF]
ABSTRACT Objective To determine the prevalence, case‐fatality rate, and primary disease processes associated with corrected hypochloremia (hypo[Cl−]) in dogs and cats. Design Single‐center retrospective study. Setting Electronic medical records were reviewed to identify dogs and cats with at least one chloride and sodium concentration measured ...
Ueda Y, Epstein SE, Hopper K.
europepmc +2 more sources
Retrospective Evaluation of the Prognosis and Prevalence of Hyperchloremia in Dogs and Cats. [PDF]
ABSTRACT Objective To determine the prevalence, case‐fatality rate, and primary disease processes associated with high corrected chloride concentration (hyper[Cl−]) in dogs and cats. Design Single‐center retrospective study. Setting Electrical medical records were reviewed to identify dogs and cats with at least one chloride and sodium concentration ...
Ueda Y, Epstein SE, Hopper K.
europepmc +2 more sources
Safety, Efficacy and Doxorubicin Pharmacokinetics During Cannabidiol/Cannabidiolic Acid Rich Hemp Oil Use in Dogs With Lymphoma Undergoing CHOP Chemotherapy. [PDF]
ABSTRACT Background The safety of oral cannabidiol (CBD) and cannabidiolic acid (CBDA)‐rich hemp oil supplementation in dogs with cancer receiving chemotherapy has not been investigated. Objectives To evaluate the safety, tolerability, and influence on doxorubicin exposure over time of oral CBD/CBDA‐rich hemp oil supplementation in dogs diagnosed with ...
Lejeune A +5 more
europepmc +2 more sources
Characterisation of localised pigment accumulation in brains of eastern grey kangaroos (Macropus giganteus) after clinical disease due to chronic Phalaris species toxicosis. [PDF]
A progressive tremorgenic syndrome characterised by ataxia and head nodding is well documented in sheep and cattle affected by chronic Phalaris toxicosis (CPT), and is increasingly documented in the eastern grey kangaroo {(EGK), Macropus giganteus} in southeastern Australia.
El-Hage C +7 more
europepmc +2 more sources
Evaluation of adverse events in small-breed dogs treated with maropitant and a single dose of doxorubicin. [PDF]
Abstract Background The recommended doxorubicin (DOX) dose for small dogs is 1 mg/kg. Recent data suggest that DOX‐induced gastrointestinal (GI) toxicosis can be reduced with maropitant treatment. Objectives To investigate the incidence of adverse events (AEs) in small‐breed dogs administered a single 25 mg/m2 DOX followed by administration of ...
Matsuyama F +5 more
europepmc +2 more sources
Delayed Zinc Phosphide Toxicosis in a Dog. [PDF]
ABSTRACT Objective Zinc phosphide is a widely used, commercial, non‐anticoagulant rodenticide. However, there is a lack of detailed information in veterinary literature regarding its toxic effects. The purpose of this case report is to provide a comprehensive description of toxicosis caused by zinc phosphide in a dog that underwent early ...
van Schie S, Hardjo S, Haworth M.
europepmc +2 more sources
Description of lesions in lambs intoxicated with sodium selenite included in intraruminal boluses: Lambs intoxicated with selenium. [PDF]
This study evidenced the main lesions related to selenium poisoning in lambs supplemented with selenium through intraruminal boluses. The main organs affected were the lung, heart, liver, kidney, thymus, thyroid gland and reticulo‐rumen. Abstract Selenium is an essential micronutrient for ruminants, which participates in the optimal functioning of ...
Serratos MJH +5 more
europepmc +2 more sources
There is a growing recognition of the harmful effects of lead exposure on avian and mammalian scavengers. This can lead to both lethal and non‐lethal effects which may negatively impact wildlife populations. Our objective was to assess medium‐term lead exposure in wild Tasmanian devils (Sarcophilus harrisii).
DJ Hutchinson +5 more
wiley +1 more source
Abstract Cyclophosphamide (CP) is an alkylating agent commonly included in multi‐drug treatment protocols for canine cancer. As a prodrug, CP requires hepatic metabolism for activation to the intermediate compound 4‐hydroxycyclophosphamide (4‐OHCP) which then spontaneously forms alkylating phosphoramide mustard.
Sridhar Veluvolu +5 more
wiley +1 more source
Evaluation of zoledronate for the treatment of canine stage III osteosarcoma: A phase II study
This single institutional phase IIa trial investigated the use of single agent zoledronate in 11 dogs with stage III osteosarcoma. Stable disease was achieved in 2 of 8 dogs available for response assessment (median progression free survival = 28 days). Adverse events were reported in 4 dogs, including conjunctivitis, fever, and hypocalcemia.
Ashley A. Smith +5 more
wiley +1 more source

