Results 11 to 20 of about 113,320 (229)
Toxoplasma effectors targeting host signaling and transcription [PDF]
Clinical Microbiology Reviews, 2017 Early electron microscopy studies revealed the elaborate cellular features that define the unique adaptations of apicomplexan parasites. Among these were bulbous rhoptry (ROP) organelles and small, dense granules (GRAs), both of which are secreted during
Ajioka JA +23 more
core +3 more sources
Plasma membrane association by N-acylation governs PKG function in Toxoplasma gondii [PDF]
mBio, 2017 Cyclic GMP (cGMP)-dependent protein kinase (protein kinase G [PKG]) is essential for microneme secretion, motility, invasion, and egress in apicomplexan parasites, However, the separate roles of two isoforms of the kinase that are expressed by some ...
Brown, Kevin M +2 more
core +3 more sources
A latent ability to persist: differentiation in Toxoplasma gondii [PDF]
Cellular and Molecular Life Sciences, 2018 A critical factor in the transmission and pathogenesis of Toxoplasma gondii is the ability to convert from an acute disease-causing, proliferative stage (tachyzoite), to a chronic, dormant stage (bradyzoite).
Jeffers, Victoria +3 more
core +2 more sources
The pathogenicity and virulence of Toxoplasma gondii
Virulence, 2021 Toxoplasma gondii is a parasitic protist infecting a wide group of warm-blooded animals, ranging from birds to humans. While this infection is usually asymptomatic in healthy individuals, it can also lead to severe ocular or neurological outcomes in ...
Syrian G. Sanchez, Sébastien Besteiro
semanticscholar +1 more source
mBio, 2022 Globally, approximately one out of three people become infected with the obligate intracellular parasite Toxoplasma. These infections are typically asymptomatic but can cause severe disease and mortality in immunocompromised individuals.
Dulcemaria Hernandez +4 more
semanticscholar +1 more source
The life-cycle of Toxoplasma gondii reviewed using animations
Parasites & Vectors, 2020 Toxoplasma gondii is a protozoan parasite that is the causative agent of toxoplasmosis, an infection with high prevalence worldwide. Most of the infected individuals are either asymptomatic or have mild symptoms, but T. gondii can cause severe neurologic
M. Attias +5 more
semanticscholar +1 more source
Adverse outcomes associated with the treatment of Toxoplasma infections
Scientific Reports, 2021 Adverse outcomes associated with the treatment of Toxoplasma gondii infections in patients with various health backgrounds have not been characterized.
A. Shammaa +2 more
semanticscholar +1 more source
Scientific Reports, 2020 Efficient health-care for pregnant women require accurate data on the prevalence of toxoplasmosis in pregnancy at global, regional, and country levels.
J. Bigna +7 more
semanticscholar +1 more source
Seroprevalence of Toxoplasma-IgA and its Relation to Serum IL-4 Level Among Pregnant Women. [PDF]
Kirkuk Journal of Science, 2018 Toxoplasmosis is caused by infection with the parasite Toxoplasma gondii. It is one of the most common parasitic infections in humans and is most typically asymptomatic.
Sanarya Tawfiq +2 more
doaj +1 more source
Defining host–pathogen interactions employing an artificial intelligence workflow
eLife, 2019 For image-based infection biology, accurate unbiased quantification of host–pathogen interactions is essential, yet often performed manually or using limited enumeration employing simple image analysis algorithms based on image segmentation. Host protein
Daniel Fisch +7 more
doaj +1 more source