Vaccines against toxoplasma gondii : challenges and opportunities [PDF]
, 2009 Development of vaccines against Toxoplasma gondii infection in humans is of high priority, given the high burden of disease in some areas of the world like South America, and the lack of effective drugs with few adverse effects.
Jongert, Erik +4 more
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Comparative Immunopathology of Toxoplasma gondii Natural Infections in Marmosets (Callithrix spp.) and Howler Monkeys (Alouatta spp.), Brazil. [PDF]
J Med PrimatolABSTRACT Introduction Neotropical primates (NTPs) present varying susceptibility to toxoplasmosis caused by Toxoplasma gondii, but their immunopathogenic responses remain poorly understood. Materials and Methods Local immune responses were characterized in the liver, spleen, and central nervous system (CNS) of 50 naturally infected NTPs (31 Callithrix ...
Pellegrino M +9 more
europepmc +2 more sources
Serosurvey of Toxoplasmosis Among Drug Users in Fars Province, Southern Iran: A Cross-Sectional Study. [PDF]
Health Sci RepABSTRACT Background and Aims Toxoplasma gondii is a widespread zoonotic protozoan that poses significant health risks, particularly to immunocompromised individuals. Although generally asymptomatic, toxoplasmosis can lead to severe neurological complications and behavioral disorders.
Cheraghi MR +10 more
europepmc +2 more sources
Current Biology, 2018 Putting cat lovers on notice: Toxoplasma gondii is here to control your brain…or is it? Kochanowsky and Koshy shine the spotlight on this notorious pathogen.
Joshua A, Kochanowsky, Anita A, Koshy
openaire +2 more sources
BMJ, 1995 The dual role of small rodents and domestic cats in the natural course of toxoplasma infection has been known for some 25 years,1 but the nature of the interplay between the protozoan and its human host remains elusive. Nowhere is this more evident than in ocular toxoplasmosis.
J, Hay, G N, Dutton
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Maternal inheritance and stage-specific variation of the apicoplast in Toxoplasma gondii during development in the intermediate and definitive host [PDF]
, 2005 The structure and location of Toxoplasma gondii apicoplasts were examined in intermediate and definitive hosts and shown to vary in a stage-specific manner.
Henriquez, F L +7 more
core +4 more sources
Seroprevalence of <i>Toxoplasma gondii</i>, Rubella Virus, Cytomegalovirus, and Herpes Simplex Virus Among Children and Women in Bhutan's National Referral Hospital: A Cross-Sectional Study. [PDF]
Public Health ChallCongenital infections caused by Toxoplasma gondii, rubella virus, cytomegalovirus, and herpes simplex virus were assessed in 624 children and women at JDWNRH (2019–2022). HSV (83.8%) and CMV (82.7%) were most prevalent, whereas T. gondii was the lowest (14.7%).
Norbu K +8 more
europepmc +2 more sources
Case Reports in Ophthalmology, 2022 Neuroretinitis is an inflammatory condition with rapid unilateral vision loss, optic disc edema, and macular star formation. While neuroretinitis is commonly due to infectious causes such as <i>Bartonella henselae</i>, neuroretinitis due to toxoplasmosis is uncommon.
Christine Hsu +2 more
openaire +3 more sources
Changing climate-changing pathogens: Toxoplasma gondii in North-Western Europe [PDF]
, 2009 In this review, we describe the effects of global climate change for one specific pathogen: the parasite Toxoplasma gondii. It is postulated that an increase of T.
Meerburg, B.G. +3 more
core +1 more source
Wellcome Open Research, 2019 Background: Infections cause the production of inflammatory cytokines such as Interferon gamma (IFNγ). IFNγ in turn prompts the upregulation of a range of host defence proteins including members of the family of guanylate binding proteins (Gbps).
Barbara Clough +7 more
doaj +1 more source