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Toxoplasma is an extremely successful intracellular parasite and important human pathogen. Upon infection of a new cell, Toxoplasma establishes a replicative vacuole and translocates parasite effectors across this vacuole to function from the host ...
Alicja M. Cygan +5 more
semanticscholar +1 more source
Significant familial differences in the frequency of abortion and Toxoplasma gondii infection within a flock of Charollais sheep [PDF]
A study was carried out to investigate the frequencies of abortion and congenital Toxoplasma gondii infection within 27 families (765 individuals) of a pedigree Charollais sheep flock maintained on a working farm in Worcestershire, UK, since 1992 ...
Duncanson, P +6 more
core +2 more sources
Toxoplasma Lymphadenopathy in an Immunocompetent Host
Toxoplasma infection can be congenital or acquired. Infection with Toxoplasma gondii can result in multi-organ involvement in immunocompromised patients; whereas in immunocompetent patients, it usually remains asymptomatic.
Sanjay Kumar Mandal +3 more
doaj +1 more source
Sensitive detection systems for infectious agents in xenotransplantation*
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley +1 more source
Toxoplasma gondii Infection in Immunocompromised Patients: A Systematic Review and Meta-Analysis
Toxoplasma gondii has been suggested as an important opportunistic pathogen in immunocompromised patients. We conducted a global meta-analysis to assess the prevalence and odds ratios (ORs) of T.
Zedong Wang +9 more
semanticscholar +1 more source
Protein import into the endosymbiotic organelles of apicomplexan parasites [PDF]
The organelles of endosymbiotic origin, plastids, and mitochondria, evolved through the serial acquisition of endosymbionts by a host cell. These events were accompanied by gene transfer from the symbionts to the host, resulting in most of the organellar
Fellows, Justin +3 more
core +1 more source
Toxoplasma GRA15 limits parasite growth in IFNγ-activated fibroblasts through TRAF ubiquitin ligases
The protozoan parasite Toxoplasma gondii lives inside a vacuole in the host cytoplasm where it is protected from host cytoplasmic innate immune responses.
D. Mukhopadhyay +4 more
semanticscholar +1 more source
Immunosuppression caused by parasitic infections represents the foremost way by which the parasites overcome or escape the host’s immune response. Glucan is a well-established natural immunomodulator with the ability to significantly improve immune ...
Vetvicka V., Fernandez-Botran R.
doaj +1 more source
Incidence of symptomatic toxoplasma eye disease: aetiology and public health implications. [PDF]
Ocular disease is the commonest disabling consequence of toxoplasma infection. Incidence and lifetime risk of ocular symptoms were determined by ascertaining affected patients in a population-based, active reporting study involving ophthalmologists ...
Dunn, DT +8 more
core +2 more sources
Innate, adaptive, and cell-autonomous immunity against Toxoplasma gondii infection
Hosts have been fighting pathogens throughout the evolution of all infectious diseases. Toxoplasma gondii is one of the most common infectious agents in humans but causes only opportunistic infection in healthy individuals.
Miwa Sasai, Masahiro Yamamoto
semanticscholar +1 more source

