Results 71 to 80 of about 87,673 (242)

Fetal Intracranial Hemorrhage: What to Tell Expecting Parents?

Prenatal Diagnosis, EarlyView.
ABSTRACT To review the classification, epidemiology, etiology, prenatal diagnostic approach, and neurodevelopmental outcomes of fetal intracranial hemorrhage (ICH), and to provide clinicians with a practical, fetal‐specific framework for investigating and counseling families facing this diagnosis.
Shiri Shinar, Yada Kunpalin, Elka Miller
wiley   +1 more source

Selection at a single locus leads to widespread expansion of toxoplasma gondii lineages that are virulent in mice [PDF]

, 2009
The determinants of virulence are rarely defined for eukaryotic parasites such as T. gondii, a widespread parasite of mammals that also infects humans, sometimes with serious consequences.
Sonya Taylor, James W Ajioka, Khan, A., James W. Ajioka, Taylor, Sonya, L David Sibley, Rosenthal Benjamin M., Ajioka, James W, Khan Asis, L. David Sibley, Taylor, S., Rosenthal, Benjamin M, Benjamin M Rosenthal, Sibley, L. David, Taylor Sonya, Ajioka James W., Sibley L. David, Sibley, L.D., Khan, Asis, Asis Khan, Benjamin M. Rosenthal, Rosenthal, B.M., Ajioka, J.W.   +22 more
core   +2 more sources

Comprehensive analysis of microtubule‐inhibiting herbicides reveals shared subcellular phenotypes and distinct resistance profiles

Pest Management Science, EarlyView.
Using cellular phenotyping and resistance profiling, we show that herbicides across the Herbicide Resistance Action Committee (HRAC) Groups 3 and 23 induce indistinguishable, dose‐dependent microtubule defects. Resistance patterns, rather than cellular phenotypes, reveal distinct sites of action and support reclassifying Group 3 as α‐tubulin binders ...
Katharina Kaprocki, Jennifer Blau, Michael Betz, Jessica Knox, Jens Lerchl, Philipp Johnen, Selene Garcia‐Hernandez   +6 more
wiley   +1 more source

Toxoplasma gondii infection drives conversion of NK cells into ILC1-like cells

eLife, 2019
Innate lymphoid cells (ILCs) were originally classified based on their cytokine profiles, placing natural killer (NK) cells and ILC1s together, but recent studies support their separation into different lineages at steady-state.
Eugene Park, Swapneel Patel, Qiuling Wang, Prabhakar Andhey, Konstantin Zaitsev, Sophia Porter, Maxwell Hershey, Michael Bern, Beatrice Plougastel-Douglas, Patrick Collins, Marco Colonna, Kenneth M Murphy, Eugene Oltz, Maxim Artyomov, L David Sibley, Wayne M Yokoyama   +15 more
doaj   +1 more source

Epidemiological distribution of MRI‐based presumptive imaging diagnoses in a large general population of cats with suspected epileptic seizures

Veterinary Record, EarlyView.
Abstract Background The reported prevalence of feline idiopathic epilepsy (IE) and presumptive imaging diagnoses based on magnetic resonance imaging (MRI) varies depending on factors such as differences between primary care versus referral study populations.
Anna Knebel, Sebastian Meller, Julien Labruyère, Holger A. Volk   +3 more
wiley   +1 more source

Profiling of myristoylation in Toxoplasma gondii reveals an N-myristoylated protein important for host cell penetration

eLife, 2020
N-myristoylation is a ubiquitous class of protein lipidation across eukaryotes and N-myristoyl transferase (NMT) has been proposed as an attractive drug target in several pathogens.
Malgorzata Broncel, Caia Dominicus, Luis Vigetti, Stephanie D Nofal, Edward J Bartlett, Bastien Touquet, Alex Hunt, Bethan A Wallbank, Stefania Federico, Stephen Matthews, Joanna C Young, Edward W Tate, Isabelle Tardieux, Moritz Treeck   +13 more
doaj   +1 more source

Biogenesis of the inner membrane complex is dependent on vesicular transport by the alveolate specific GTPase Rab11B [PDF]

, 2010
Apicomplexan parasites belong to a recently recognised group of protozoa referred to as Alveolata. These protists contain membranous sacs (alveoli) beneath the plasma membrane, termed the Inner Membrane Complex (IMC) in the case of Apicomplexa.
Langsley, G, Bernardo J. Foth, Ferguson, D.J. P., Ferguson, DJ, Markus Meissner, David J. P. Ferguson, Foth, B.J., Carolina Agop-Nersesian, Langsley, G., Agop-Nersesian, C, Meissner, M, Saskia Egarter, Meissner, M., Egarter, S., Sibley, L.D., Egarter, S, Bernardo J Foth, Gordon Langsley, Agop-Nersesian, C., David J P Ferguson, Foth, BJ   +20 more
core   +1 more source

Comprehensive evaluation of metagenomic next‐generation sequencing for pathogen identification in patients with suspected infection: Establishment of a standardized validation workflow

VIEW, EarlyView.
Comprehensive evaluation of metagenomic next‐generation sequencing for pathogen identification in patients with suspected infection: Establishment of a standardized validation workflow. Abstract Metagenomic next‐generation sequencing (mNGS) enables unbiased identification of pathogens directly from clinical specimens. Despite its growing application in
Wen Shu, Qiaomei Guo, Han Yang, Huiqin Jiang, Chunyan He, Xueqing Wang, Yuting Fang, Yue Yin, Liwen Zhong, Zhijing Zhao, Jiatao Lou, Lin Wang   +11 more
wiley   +1 more source

Secuelas clínicas y neurodesarrollo de pacientes pediátricos con toxoplasmosis congénita en un centro de cuarto nivel

Biomédica: revista del Instituto Nacional de Salud
Introducción. La toxoplasmosis congénita es una enfermedad parasitaria de importante prevalencia a nivel mundial, con gran morbilidad y afectación del neurodesarrollo en pacientes pediátricos. Objetivo. Describir las secuelas y valorar el neurodesarrollo
Sebastián Posada-Bustos, Ana Cristina Mariño, Eugenia Espinosa-García   +2 more
doaj   +1 more source

Putting Rodents at the Center of One Health Programs: A Narrative Synthesis

Integrative Zoology, EarlyView.
Rodents link human, animal, and environmental health across diverse ecosystems. Rodent diversity underpins both zoonotic disease risk and ecosystem function. Environmental change reshapes rodent communities and spillover dynamics. Rodents act as reservoirs, amplifiers, and sentinels of emerging pathogens.
Steven R. Belmain
wiley   +1 more source