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Congenital toxoplasmosis is a parasitic disease caused by the transmission of the protozoan Toxoplasma gondii during pregnancy that can potentially cause severe consequences for the fetus or neonates.
David Richer Araujo Coelho +4 more
semanticscholar +1 more source
Background Toxoplasmosis endangers the unborn child if its infectious agent - toxoplasma gondii - is transmitted transplacentally during pregnancy. Although this condition occurs in all parts of the world and represents a major public health burden, no ...
Dörthe Brüggmann +4 more
doaj +1 more source
Why prevent, diagnose and treat congenital toxoplasmosis?
Evidence that prevention, diagnosis and treatment of toxoplasmosis is beneficial developed as follows: anti-parasitic agents abrogate Toxoplasma gondiitachyzoite growth, preventing destruction of infected, cultured, mammalian cells and cure active ...
Rima McLeod +4 more
doaj +1 more source
Treatment for congenital toxoplasmosis: finding out what works [PDF]
Evidence for the effectiveness of prenatal or postnatal treatment for congenital toxoplasmosis will be critical to guide policy about prenatal and neonatal screening over the next 10 years, let alone the next 100.
Gilbert, R
core +3 more sources
QuilA-adjuvanted T. gondii lysate antigens trigger robust antibody and IFNγ+ T cell responses in pigs leading to reduction in parasite DNA in tissues upon challenge infection [PDF]
Toxoplasma gondii is an intracellular parasite of all mammals and birds, responsible for toxoplasmosis. In healthy individuals T. gondii infections mostly remain asymptomatic, however this parasite causes severe morbidity and mortality in ...
Cox, Eric +6 more
core +2 more sources
Toxoplamosis is a parasitic zoonosis which occurs worldwide, but is prevalent in Europe, South America and Africa. When infection occurs for the first time during pregnancy, mother to child transmission of the parasite can cause congenital toxoplasmosis.
Lina Bollani, Mauro Stronati
doaj +1 more source
Toxoplasma effectors targeting host signaling and transcription [PDF]
Early electron microscopy studies revealed the elaborate cellular features that define the unique adaptations of apicomplexan parasites. Among these were bulbous rhoptry (ROP) organelles and small, dense granules (GRAs), both of which are secreted during
Ajioka JA +23 more
core +2 more sources
We assessed clinical and serologic findings in 25 infants with congenital toxoplasmosis born to mothers treated during pregnancy in the United States. Results indicate a lower prevalence of eye findings and hydrocephalus in the group of infants born to ...
T. Olariu +4 more
semanticscholar +1 more source
The cost-effectiveness of neonatal versus prenatal screening for congenital toxoplasmosis
Background Congenital Toxoplasmosis (CT) can have severe consequences. France, Austria, and Slovenia have prenatal screening programs whereas some other countries are considering universal screening to reduce congenital transmission and severity of ...
C. Binquet +9 more
semanticscholar +1 more source
ABSTRACT Background Classifying abnormal tongue movements is challenging due to their varied presentations and limited visibility compared to other body parts. Accurate identification of the phenomenology guides physical examination and can point to specific diagnoses.
Nathaniel Bendahan +4 more
wiley +1 more source

