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Toxoplasmosis: Current and Emerging Parasite Druggable Targets [PDF]

open access: yesMicroorganisms, 2021
Toxoplasmosis is a prevalent disease affecting a wide range of hosts including approximately one-third of the human population. It is caused by the sporozoan parasite Toxoplasma gondii (T.
Marwan El Sabban   +2 more
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Toxoplasmosis

Primary Care Update for OB/GYNS, 2001
Toxoplasma gondii is a unicellular protozoan. The definitive hosts, cats, produce hardy oocysts and sporozoites. Ingestion by a nonfeline leads to the formation of tachyzoites acutely, which cause parasitemia and further dissemination, and bradyzoites, which lead to latent infection with the formation of tissue cysts in skeletal muscle, heart muscle ...
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Toxoplasmosis

Seminars in Fetal and Neonatal Medicine, 2007
Infections with Toxoplasma gondii occur worldwide, but are especially prevalent in Europe, South America and Africa. The primary problem for the diagnosis of T. gondii infection is long-lasting IgM-antibodies, thus the presence of T. gondii-specific IgM-antibodies do not necessarily indicate an acute infection.
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Toxoplasmosis

Veterinary Clinics of North America: Small Animal Practice, 1987
Infection with T. gondii can have devastating effects on the development of the unborn human fetus. As veterinarians or physicians, we should be able to accurately assess the true risk of exposure of a person to meat-borne tissue cysts or to oocysts based on the age, health, roaming and feeding habits of their cats, and the occupational or recreational
J R, August, T M, Chase
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Toxoplasmosis

Veterinary Clinics of North America: Small Animal Practice, 2000
Toxoplasmosis in dogs and cats can cause chorioretinitis, anterior uveitis, or both. Ocular lesions are a common manifestation of generalized toxoplasmosis. The prevalence of toxoplasmosis as a cause of idiopathic anterior uveitis in cats is not clear, although there is a significant association between exposure to T. gondii and feline anterior uveitis.
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Toxoplasmosis

Current Opinion in Ophthalmology, 2006
The purpose of this review is to update the latest information on a long-recognized infectious disease, ocular toxoplasmosis.Topics include how the disease is acquired, how to make a clinical diagnosis, and what laboratory tests to order when the diagnosis is not clear.
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Toxoplasmosis

Developmental Medicine & Child Neurology, 1962
SUMMARYSerological evidence indicates that infection with the protozoon Toxoplasma gondii is of frequent occurrence among a wide variety of warm‐blooded animals, including man. The incidence of infection varies in different parts of the world, tending to be greatest in places with warm, moist climates.
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Toxoplasmosis

Pediatrics In Review, 1991
Toxoplasma gondii is an obligate intracellular parasite capable of infecting humans and a variety of other warm-blooded animals. The organism is distributed widely in nature and may infect as many as 1 of 3 persons worldwide. Most Toxoplasma infections are either asymptomatic or otherwise benign; notable exceptions include the infections of the ...
B J, Freij, J L, Sever
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Toxoplasmosis*

Journal of Small Animal Practice, 1963
Abstract— A brief history of toxoplasmosis is given together with a description of the different clinical manifestations in man.An explanation of the different types of diagnostic tests available for this condition, with their various difficulties is presented.
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Toxoplasmosis

Journal of the American Veterinary Medical Association, 1986
Toxoplasma gondii is a protozoan parasite that infects most species of warm-blooded animals, including human beings. Infection in cats is of particular interest because Felidae (domestic and wild) are the only known definitive hosts for T. gondii and thus are the main reservoirs of infection. Clinical and public health aspects of T.
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