Results 181 to 190 of about 149,070 (296)

Real world predictors of response and 24-month survival in high-grade TP53-mutated myeloid neoplasms [PDF]

Amandeep Kaur, Alexandra E. Rojek, Emily Symes, Mariam T. Nawas, Anand Patel, Jay Patel, Payal Sojitra, Barina Aqil, Madina Sukhanova, Megan E. McNerney, Leo P. Wu, Aibek Akmatbekov, Jeremy Segal, Melissa Y. Tjota, Sandeep Gurbuxani, Jason X. Cheng, Su Yeon Yeon, Harini V. Ravisankar, Carrie Fitzpatrick, Angela M. Lager, Michael W. Drazer, Caner Saygin, Pankhuri Wanjari, Panagiotis Katsonis, Olivier Lichtarge, Jane E. Churpek, Sharmila B. Ghosh, Ami B. Patel, Madhu P. Menon, Daniel A. Arber, Peng Wang, Girish Venkataraman   +31 more
openalex   +1 more source

Organoids and organ‐on‐a‐chip models for investigating the pathophysiology of the human reproductive system

Interdisciplinary Medicine, EarlyView.
Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang, Shiwen Deng, Fangfang Jin, Jiayao Qu, Xiang Fan, Peng Chen, Xinrong Fan   +6 more
wiley   +1 more source

Co-occurrence of High-Risk Myelodysplastic Syndrome With a Complex Karyotype/TP53 Mutation and IgG Lambda Monoclonal Gammopathy of Undetermined Significance [PDF]

Marwa Mir, Wajeeha Aiman, Esther Baah, Gunwant Guron, Hamid Shaaban   +4 more
openalex   +1 more source

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

Journal of Applied Toxicology, EarlyView.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza, Lara Rodrigues De Andrade, Tatiana da Silva Souza   +2 more
wiley   +1 more source

TP53-aberrated CLL: is BTK inhibitor monotherapy enough? [PDF]

Blood Adv
Niemann CU.
europepmc   +1 more source

TP53 NP_000537.3:p.G245S [PDF]

, 2020
openaire   +1 more source

Knockdown of TOP2A reverses cisplatin resistance in ovarian cancer by inhibiting EMT via ferroptosis mediated by the TP53/GPX4/SLC7A11 axis [PDF]

Xinyue Liu, Junxia Wang, Yang‐Yu Liu, Yan Han, Zhihai Qin, Yu Wang, Shouhong Gao, Xinghua Li, Yuping Suo   +8 more
openalex   +1 more source

Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer

, 2020
Fang Hu, Jayne A. Barbour, Rebecca C. Poulos, Riku Katainen, Lauri A. Aaltonen, Jason W.H. Wong   +5 more
openalex   +1 more source

Bisphenol A Induces DNA Damage and Differential Cytotoxicity in Thyroid Cells: High‐Dose Effects Challenge Regulatory Thresholds

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA), a ubiquitous environmental endocrine disruptor, has been implicated in carcinogenesis; however, its effects on thyroid cells remain unclear. This study investigated BPA‐induced cytotoxicity and genotoxicity in thyroid cell lines, including normal follicular (Nthy‐ori 3‐1), papillary carcinoma (TPC‐1 and BCPAP) and anaplastic
Izabela Fernanda Dal' Bó, Natássia Elena Bufalo, Valdemar Máximo, Laura Sterian Ward   +3 more
wiley   +1 more source

Targeting tumor suppressor gene co-mutations in EGFR-mutant nonsmall cell lung cancer: How ACROSS2 sharpens the case for early intensification. [PDF]

CA Cancer J Clin
Gunturu KS, Khan H, de Lima Lopes G.
europepmc   +1 more source