Results 21 to 30 of about 12,869 (95)

Identification of Circulating miR-762 as a Novel Diagnostic and Prognostic Biomarker for Non-Small Cell Lung Cancer

Technology in Cancer Research and Treatment, 2020
Background: MicroRNAs (miRNAs) have been demonstrated to play critical roles in tumorigenesis of non-small cell lung cancer (NSCLC), and circulating miRNAs are a valuable source of biomarkers for the clinical management of NSCLC.
Lei Chen, Yunxia Li, Jing Lu
semanticscholar   +1 more source

miR-762 regulates the proliferation and differentiation of retinal progenitor cells by targeting NPDC1

Cell Cycle, 2020
Retinal degenerations, which lead to irreversible decline in visual function, are still no effective recovery treatments. Currently, retinal progenitor cell (RPC) transplantation therapy is expected to provide a new approach to treat these diseases ...
Huiqin Gao, Ni Ni, Dandan Zhang, Yuyao Wang, Zhimin Tang, Na Sun, Yahan Ju, Xiaochan Dai, Yidan Zhang, Yan Liu, P. Gu   +10 more
semanticscholar   +1 more source

Mitochondrial miR-762 regulates apoptosis and myocardial infarction by impairing ND2

Cell Death and Disease, 2019
Mitochondrial dysfunction plays a major role in the pathogenesis of cardiovascular diseases. MicroRNAs (miRNAs) are small RNAs that act as negative regulators of gene expression, but how miRNAs affect mitochondrial function in the heart is unclear. Using
K. Yan, T. An, M. Zhai, Y. Huang, Qi Wang, Yunhong Wang, Rong-cheng Zhang, Tao Wang, Jing Liu, Yuhui Zhang, Jian Zhang, Kun Wang   +11 more
semanticscholar   +1 more source

CircTRNC18 inhibits trophoblast cell migration and epithelial–mesenchymal transition by regulating miR-762/Grhl2 pathway in pre-eclampsia

RNA Biology, 2019
Dysfunctions of epithelial–mesenchymal transition (EMT)-regulated cell migration and invasion have been involved in the pathogenesis of pre-eclampsia (PE). However, the role of circRNAs in EMT of PE has not been widely investigated.
Xue-Yan Shen, Lili Zheng, Jing Huang, Hongfang Kong, Yanxiang Chang, F. Wang, H. Xin   +6 more
semanticscholar   +1 more source

The BRD4 Inhibitor I-BET-762 Reduces HO-1 Expression in Macrophages and the Pancreas of Mice

International Journal of Molecular Sciences
In pancreatic cancer, the tumor microenvironment (TME) accounts for up to 90% of the tumor mass. Pancreatitis, characterized by the increased infiltration of macrophages into the pancreas, is a known risk factor for pancreatic cancer.
Ana S Leal, K. Liby
semanticscholar   +1 more source

miR-762 activation confers acquired resistance to gefitinib in non-small cell lung cancer

BMC Cancer, 2019
Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) (e.g. gefitinib) currently remain the first-line treatment for patients with advanced non-small-cell lung cancer (NSCLC) with activating EGFR mutation. However, acquired resistance
Peng Ge, Lei Cao, Xin Chen, R. Jing, Wanxia Yue   +4 more
semanticscholar   +1 more source

Origin and accumulation models of ultra-low permeability-tight sandstone (gravel) gas in Bohai Bay Basin, China

Journal of Natural Gas Geoscience, 2022
Ultra-low permeability–tight sandstone (gravel) gas reservoir is an important exploration target for natural gas both domestically and internationally.
Jianying Guo, Xuening Qi, Lianhua Hou, Aisheng Hao, Xu Zeng, Shiguo Lin, Xiugang Pu, Zengye Xie, Yifeng Wang, Xiaobo Wang, Dawei Chen   +10 more
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Analysis on distribution and main controlling factors of OM carbonization in marine shale in the Sichuan Basin of China and its periphery

Journal of Natural Gas Geoscience, 2022
The distribution and main controlling factors of the organic matter carbonization points/zones of over-mature marine shale are important issues for shale gas exploration.
Yuman Wang, Guoqi Wei, Junjun Shen, Zhen Qiu, Xinjing Li, Qin Zhang, Leifu Zhang, Canhui Wang, Wen Liu   +8 more
doaj  

circLPAR1 is a novel biomarker of prognosis for muscle-invasive bladder cancer with invasion and metastasis by miR-762.

Oncology Letters, 2019
Circular RNAs (circRNAs) are a specific form of non-coding RNAs, that serve a pivotal role in the development of human diseases, including Alzheimer's disease and cancer; however, only a few are known with respect to cancer.
G. Lin, Haoyue Sheng, Huyang Xie, Qiupeng Zheng, Yijun Shen, G. Shi, D. Ye   +6 more
semanticscholar   +1 more source

Development characteristics and main control factors of deep clastic reservoirs of the Xiaganchaigou Formation in the northern marin of the Qaidam Basin, China

Journal of Natural Gas Geoscience, 2022
The deep strata of the northern margin of the Qaidam Basin are currently unexplored and have high resource potential. To clarify the characteristics and control factors of the deep sandstone reservoir in the study area, a comprehensive investigation of ...
Jixian Tian, Baoqiang Ji, Xu Zeng, Yetong Wang, Yaoliang Li, Guoqiang Sun   +5 more
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