Results 71 to 80 of about 2,438 (219)

Targeting Kinetoplastid Parasites with ProTide Prodrugs: A Proof‐of‐Concept Study

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
Neglected tropical diseases (NTDs) remain a major global health challenge, particularly in low‐ and middle‐income countries. Kinetoplastid parasites causing Chagas disease, leishmaniasis, and African trypanosomiasis rely on host purine salvage pathways, making nucleoside analogues attractive therapeutic candidates.
Silvester Lowe, Vishal Satikuvar, Tanjia M. Syeda, Monica Cal, Pascal Mäser, Marcel Kaiser, Hachemi Kadri   +6 more
wiley   +1 more source

Impact of Different Sources of Anthropogenic Pollution on the Structure and Distribution of Antarctic Marine Meiofauna Communities

Diversity
Human influence on Antarctic marine ecosystems is a growing concern, despite limited information being available. This study investigated the coastal meiofauna and environmental parameters of 10 locations, 4 of which served as reference points (OB1, OB2,
Débora A.A. França, Jeroen Ingels, Jonathan S. Stark, Renan B. da Silva, Flávia J.L. de França, Giovanni A.P. dos Santos   +5 more
doaj   +1 more source

High-Speed Copper Filling within High Aspect Ratio Through Holes in Polymer Substrates

International Journal of Electrochemical Science, 2013
In this work, we presented a ''bottom-up'' and a ''two-step'' electrodeposition formulas for copper filling within high aspect through polymer holes (TPHs), which are needed for integrating flexible bio-micro-electro-mechanical system (bio-MEMS) sensors ...
Q.S. Zhu, A. Toda, Y. Zhang, T. Itoh, R. Maeda   +4 more
doaj   +1 more source

Biological Degradation of Phthalates: From Bioremediation to Plastic Waste Valorization

ChemSusChem, Volume 19, Issue 7, 14 April 2026.
Phthalic acid isomers play a key role in the plastics industry, but pose significant environmental and health concerns. This review explores the microbial biodegradation of phthalates and their esters, focusing on bacterial enzymes, catabolic pathways, and cellular uptake mechanisms of phthalates.
Marco A. Pereyra‐Camacho, Isabel Pardo
wiley   +1 more source

Biological Effects of Dispersants and Dispersed Oil in Surface and Deep Ocean Species [PDF]

, 2011
Beginning with the use of industrial-strength detergents, dispersing agents have been employed in spill response for decades. The Corexit series of agents in common use today generally consist of non-ionic and/or anionic surfactants in a solvent base ...
Bejarano, Adriana C., Edge, Sara, Tjeerdema, Ronald   +2 more
core   +1 more source

Single‐cell RNA sequencing and high‐dimensional flow cytometry reveal distinct peripheral immune landscapes of type 1 autoimmune pancreatitis and pancreatic ductal adenocarcinoma

Clinical and Translational Medicine, Volume 16, Issue 4, April 2026.
Research Highlights • Illustrated the single‐cell peripheral immune landscape of AIP and its distinction from PDAC. • Identified expanded CD23+IgG4high‐switched memory B cells, Tfh cells and enhanced antigen‐presentation interactions between them. • Multi‐centre flow cytometry validated a nomogram incorporating these subsets for differential diagnosis.
Chenxiao Liu, Tianyi Che, Airu Liu, Jiaxin Wang, Qidi Yang, Yiwen Tu, Zonghao Liu, Xiaonan Shen, Xiangyi He, Tingting Gong, Ling Zhang, Zhengji Song, Junjie Fan, Yue Zeng, Wenbin Zou, Youqiong Ye, Yao Zhang, Minmin Zhang, Duowu Zou, Chunhua Zhou   +19 more
wiley   +1 more source

Identification of a Novel, Oncogenic and Targetable TPR::ABL2 Fusion Gene in T‐Cell Acute Lymphoblastic Leukaemia

eJHaem, Volume 7, Issue 2, April 2026.
ABSTRACT ABL2 rearrangements represent a subtype of acute lymphoblastic leukaemia (ALL) associated with poor prognosis and survival. This study reports a high‐risk T‐cell ALL (T‐ALL) case with a novel TPR::ABL2 gene fusion resulting from a chromosomal deletion.
Elias Lagonik, Elyse. C. Page, Laura N. Eadie, Caitlin E. Schutz, Jacqueline A. Rehn, Susan L. Heatley, Andrew S. Moore, Muirin Healy, Morag Whyte, Timothy P. Hughes, David T. Yeung, Deborah L. White   +11 more
wiley   +1 more source

Concentration of Total petroleum Hydrocarbons and Selected Heavy Metals In Soil And plant nearby Al-Nassiriya oil Refinery South of Iraq

مجلة علوم ذي قار, 2019
The present study deal with measure concentration of Total petroleum hydrocarbons (TPHs) and selected heavy metals (HMs) (Cd , Pb , Co , V, and Ni) in soil and plant phragmits austriles (cav.) nearby AL-Nassiriya  oil  refinery during  the period ...
Noora k.k., Bassim y. AL-khafaji
doaj   +4 more sources

Time-dependent performance of soil mix technology stabilized/solidified contaminated site soils. [PDF]

, 2015
This paper presents the strength and leaching performance of stabilized/solidified organic and inorganic contaminated site soil as a function of time and the effectiveness of modified clays applied in this project.
Al-Tabbaa, Abir, Wang, Fei, Wang, Hailing   +2 more
core   +1 more source

Structures of pentatricopeptide repeat proteins

Acta Crystallographica Section F, Volume 82, Issue 4, Page 101-113, April 2026.
A number of crystal, cryo‐EM and solution structures of pentatricopeptide repeat proteins have been solved, revealing details of how they interact with single‐stranded RNA and other proteins, as well as their conformational repertoire.Pentatricopeptide repeat (PPR) proteins constitute the largest family of RNA‐binding proteins in land plants, playing ...
Anuradha Pullakhandam, Crystal Cooper, Ian D. Small, Charles S. Bond   +3 more
wiley   +1 more source