Results 191 to 200 of about 8,384 (285)
Abstract Objective Current recommendations for prescribing combined oral contraceptives (COCs) to people with epilepsy are often conflicting, particularly for weak inducers of cytochrome P450 3A4. We aimed to critically review the literature and compare the antiseizure medication (ASM)‐induced changes in exposure to COC components.
Hagar Cohen +4 more
wiley +1 more source
Design of novel orthotic insoles based on partition infilling of TPMS structures. [PDF]
Lyu Y +6 more
europepmc +1 more source
Oligogenic inheritance in epilepsy: A systematic exome‐wide analysis
Abstract Objective Genetic factors contribute to the majority of epilepsies, but the exact genetic cause remains unknown in most patients. Incomplete penetrance and variable expressivity are frequent, and recent studies showed a burden of deleterious variants in epilepsy genes, suggesting a role for oligogenic inheritance.
Sarah Duerinckx +192 more
wiley +1 more source
Bioinspired Mechanical Structures for Load Bearing and Energy Absorption: Cross-Scale Design and Fabrication Strategies. [PDF]
Chen T +5 more
europepmc +1 more source
Abstract Objective A multi‐electrode array (MEA) is a powerful extracellular recording technique for long‐term monitoring of neuronal network activity. In recent years, MEA‐based assays have been applied increasingly to evaluate drug efficacy and neurotoxicity, including the assessment of anti‐seizure medications (ASMs). However, systematic comparisons
Griselda Marku +4 more
wiley +1 more source
Enthalpy-Driven Topological Programming of (TPMS)-Like Carbon Networks. [PDF]
Ma J +14 more
europepmc +1 more source
Altered cortical synchronization in photosensitive idiopathic generalized epilepsy
Abstract Objective To characterize cortical excitability and synchronization dynamics in patients with idiopathic generalized epilepsy (IGE) and photosensitivity by assessing steady‐state visual evoked potentials (SSVEPs) elicited by intermittent photic stimulation.
Alessandro Benedetto +5 more
wiley +1 more source
Structure-Property Evolution of Cubic and Gyroid PLA Scaffolds During In Vitro Degradation Under Physiologically Relevant Conditions. [PDF]
Portan DV +4 more
europepmc +1 more source
Abstract This Phase I study evaluated the safety, tolerability, and pharmacokinetics of a 30‐min topiramate injection (intravenous [IV] TPM) infusion compared with oral topiramate (oral TPM) in healthy adult participants. In this randomized, open‐label, dose escalation, crossover study with 37 healthy participants received single doses of 50, 100, or ...
Adeboye O. Bamgboye +3 more
wiley +1 more source
Modelling the Mechanical Properties of Architected Cellular Solids for Structural Applications: A Review. [PDF]
Flores Alarcón JL +5 more
europepmc +1 more source

