Results 191 to 200 of about 8,384 (285)

The effect of antiseizure medications on the exposure to combined oral contraceptives: A systematic review and network meta‐analysis

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective Current recommendations for prescribing combined oral contraceptives (COCs) to people with epilepsy are often conflicting, particularly for weak inducers of cytochrome P450 3A4. We aimed to critically review the literature and compare the antiseizure medication (ASM)‐induced changes in exposure to COC components.
Hagar Cohen   +4 more
wiley   +1 more source

Design of novel orthotic insoles based on partition infilling of TPMS structures. [PDF]

open access: yesFront Bioeng Biotechnol
Lyu Y   +6 more
europepmc   +1 more source

Oligogenic inheritance in epilepsy: A systematic exome‐wide analysis

open access: yesEpilepsia, EarlyView.
Abstract Objective Genetic factors contribute to the majority of epilepsies, but the exact genetic cause remains unknown in most patients. Incomplete penetrance and variable expressivity are frequent, and recent studies showed a burden of deleterious variants in epilepsy genes, suggesting a role for oligogenic inheritance.
Sarah Duerinckx   +192 more
wiley   +1 more source

Acute effects of anti‐seizure medications on network level dynamics: A systematic comparison using multielectrode arrays

open access: yesEpilepsia, EarlyView.
Abstract Objective A multi‐electrode array (MEA) is a powerful extracellular recording technique for long‐term monitoring of neuronal network activity. In recent years, MEA‐based assays have been applied increasingly to evaluate drug efficacy and neurotoxicity, including the assessment of anti‐seizure medications (ASMs). However, systematic comparisons
Griselda Marku   +4 more
wiley   +1 more source

Enthalpy-Driven Topological Programming of (TPMS)-Like Carbon Networks. [PDF]

open access: yesAdv Mater
Ma J   +14 more
europepmc   +1 more source

Altered cortical synchronization in photosensitive idiopathic generalized epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective To characterize cortical excitability and synchronization dynamics in patients with idiopathic generalized epilepsy (IGE) and photosensitivity by assessing steady‐state visual evoked potentials (SSVEPs) elicited by intermittent photic stimulation.
Alessandro Benedetto   +5 more
wiley   +1 more source

A Phase I study of the pharmacokinetics (PK), bioavailability, dose proportionality, safety, and tolerability of topiramate injection compared to Oral topiramate in healthy adult participants

open access: yesEpilepsia, EarlyView.
Abstract This Phase I study evaluated the safety, tolerability, and pharmacokinetics of a 30‐min topiramate injection (intravenous [IV] TPM) infusion compared with oral topiramate (oral TPM) in healthy adult participants. In this randomized, open‐label, dose escalation, crossover study with 37 healthy participants received single doses of 50, 100, or ...
Adeboye O. Bamgboye   +3 more
wiley   +1 more source

Modelling the Mechanical Properties of Architected Cellular Solids for Structural Applications: A Review. [PDF]

open access: yesMaterials (Basel)
Flores Alarcón JL   +5 more
europepmc   +1 more source

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