Three-dimensional-printed strontium-incorporated β-TCP bioceramic triply periodic minimal surface scaffolds with enhanced angiogenic and osteogenic properties. [PDF]
Regen BiomaterShan Y +13 more
europepmc +1 more source
Mechanisms of SCN2A loss of function do not predict presence or phenotype of epilepsy
Epilepsia, EarlyView.Abstract Objective SCN2A loss‐of‐function (LoF) variants are associated with epilepsy (onset age ≥ 3 months), intellectual disability (ID), and autism spectrum disorder (ASD). Despite numerous identified variants and the description of phenotypic subgroups, relationships between Nav1.2 channel dysfunction and clinical phenotypes remain unclear.
Marsha Tan +23 more
wiley +1 more source
Research Progress on Personalized Bone Implants Based on Additive Manufacturing. [PDF]
Micromachines (Basel)Gao B, Sun Z, Tong Y, Yu H, Wang F.
europepmc +1 more source
Ultra‐refractory epilepsy: The newly described entity
Epilepsia Open, EarlyView.Abstract Objective Drug‐resistant epilepsy (DRE) is defined as the failure of two antiseizure medications (ASMs) to achieve complete seizure control, affecting approximately 30% of epilepsy patients. In some cases, additional ASMs and surgical approaches are also unsuccessful.
Jan Vinklárek +13 more
wiley +1 more source
Multi-Objective Machine Learning Optimization of Cylindrical TPMS Lattices for Bone Implants. [PDF]
Biomimetics (Basel)Rezapourian M +3 more
europepmc +1 more source
Genomic and Immune Correlates of EZH2 Expression and Activity in Olfactory Neuroblastoma
Head &Neck, EarlyView.ABSTRACT Purpose Olfactory neuroblastoma (ONB) is a rare sinonasal malignancy with limited therapeutic options in the recurrent/metastatic setting; little is known regarding its responsiveness to immunotherapy. Inhibition of enhancer of zeste homolog 2 (EZH2) has been shown to improve T‐cell‐mediated killing and susceptibility to immune checkpoint ...
Elisabetta Xue +12 more
wiley +1 more source
Mechanical Performance and Energy Absorption of Ti6Al4V I-WP Lattice Metamaterials Manufactured via Selective Laser Melting. [PDF]
Materials (Basel)Yu L +8 more
europepmc +1 more source
HNSC paired sample isoform TPM values used in the Iso-kTSP analysis
, 2014 Endre Sebestyén
openalex +1 more source
The role of the gut microbiome in the regulation of high‐altitude adaptation
iMeta, EarlyView.This study is the first to elucidate mechanisms of high‐altitude adaptation from the perspective of the rumen ecosystem by using indigenous yaks and Holstein cows that have lived at high altitude since birth as comparative models. Through a systematic comparison of their rumen ecology using multi‐omics approaches—including rumen metagenomics ...
Xinyu Zhang +6 more
wiley +1 more source