Results 41 to 50 of about 18,195 (319)

Selective Laser Melting Fabrication of Porous Ti6Al4V Scaffolds With Triply Periodic Minimal Surface Architectures: Structural Features, Cytocompatibility, and Osteogenesis

Frontiers in Bioengineering and Biotechnology, 2022
The relationship between pore architecture and structure performance needs to be explored, as well as confirm the optimized porous structure. Because of the linear correlation between constant C and pore architecture, triply periodic minimal surface ...
Jia Lv, Wenxuan Jin, Wenhao Liu, Xiuyu Qin, Yi Feng, Junjun Bai, Zhuangzhuang Wu, Jian Li   +7 more
doaj   +1 more source

The relationship between copyright and contract law [PDF]

, 2010
Contracts lie at the heart of the regulatory system governing the creation and dissemination of cultural products in two respects: (1) The exclusive rights provided by copyright law only turn into financial reward, and thus incentives to creators ...
Derclaye, Estelle, Favale, Marcella, Kretschmer, Martin, Watt, Richard   +3 more
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Revealing the apparent and local mechanical properties of heterogeneous lattice: a multi-scale study of functionally graded scaffold

Virtual and Physical Prototyping, 2023
Functionally graded scaffold (FGS) can flexibly regulate the mechanical properties of bone scaffold and holds great promise for offering multifunctional responses of orthopaedic implants.
Xiangyu Zhang, Lan Jiang, Xingchen Yan, Zhipeng Wang, Xiaowei Li, Gang Fang   +5 more
doaj   +1 more source

Achieving Triply Periodic Minimal Surface Thin-Walled Structures by Micro Laser Powder Bed Fusion Process

Micromachines, 2021
Recently, triply periodic minimal surface (TPMS) lattice structures have been increasingly employed in many applications, such as lightweighting and heat transfer, and they are enabled by the maturation of additive manufacturing technology, i.e., laser ...
Shuo Qu, Junhao Ding, Xu Song
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Energy absorption of gradient triply periodic minimal surface structure manufactured by stereolithography

Reviews on Advanced Materials Science
Triply periodic minimal surface (TPMS) metamaterials possess exceptional properties not commonly found in natural materials. TPMS metamaterials are used in lightweight structures and impact energy absorption structures due to their surface geometry and ...
Liang Yingjing, He Huiyi, Yin Jun, Liu Yijie, Huang Jianzhang, Wu Zhigang, Zhai Yun, Hui David, Yan Lewei   +8 more
doaj   +1 more source

A turning point analysis of the ergodic dynamics of iterative maps

, 1997
The dynamics of one dimensional iterative maps in the regime of fully developed chaos is studied in detail. Motivated by the observation of dynamical structures around the unstable fixed point we introduce the geometrical concept of a turning point which
Diakonos, F. K., Schmelcher, P.
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Periodic minimal surfaces of cubic symmetry [PDF]

, 2003
A survey of cubic minimal surfaces is presented, based on the concept of fundamental surface patches and their relation to the asymmetric units of the space groups.
Lord, Eric A., Mackay, Alan L.
core