Results 51 to 60 of about 59,328 (159)

Hypoxic regulation of TR1 expression in HIF-1α deficient cells.

open access: yes, 2012
TR1 and HIF-1α protein levels, from (A) EMT6 cells and (B) DT cells infected with retrovirus encoding a scramble sequence (SCR) or a HIF-1α shRNA (si HIF-1α) and cultured under normoxic (Nx) or hypoxic (Hx) conditions for 12 h, were determined by western
Salvador Naranjo-Suarez (115256)   +5 more
core   +1 more source

Image_4_Highly purified and functionally stable in vitro expanded allospecific Tr1 cells expressing immunosuppressive graft-homing receptors as new candidates for cell therapy in solid organ transplantation.tif

open access: yes, 2023
The development of new strategies based on the use of Tr1 cells has taken relevance to induce long-term tolerance, especially in the context of allogeneic stem cell transplantation.
Evelyn Katy Alvarez-Salazar (8656917)   +7 more
core   +1 more source

Advances in magnetic particle imaging: evaluating magnetic microspheres and optimized acquisition parameters for high sensitivity cell tracking

open access: yesFrontiers in Imaging
IntroductionThe sensitivity and resolution of magnetic particle imaging (MPI) depend on the choice of tracer and specific imaging parameters. For cell tracking applications with MPI, both the superparamagnetic iron oxide (SPIO) tracer and the cell ...
Samantha N. Flood   +3 more
doaj   +1 more source

AI-enabled multi-disease diagnosis using low-cost CBC reports

open access: yesFrontiers in Imaging
Complete blood count (CBC) reports are widely used in clinical settings to determine hematological disorders at early stages, offering a cost-effective and rapid alternative to expensive, time-consuming disease-specific tests.
Maria Bibi   +7 more
doaj   +1 more source

Image_1_Highly purified and functionally stable in vitro expanded allospecific Tr1 cells expressing immunosuppressive graft-homing receptors as new candidates for cell therapy in solid organ transplantation.tif

open access: yes, 2023
The development of new strategies based on the use of Tr1 cells has taken relevance to induce long-term tolerance, especially in the context of allogeneic stem cell transplantation.
Evelyn Katy Alvarez-Salazar (8656917)   +7 more
core   +1 more source

Image_2_Highly purified and functionally stable in vitro expanded allospecific Tr1 cells expressing immunosuppressive graft-homing receptors as new candidates for cell therapy in solid organ transplantation.tif

open access: yes, 2023
The development of new strategies based on the use of Tr1 cells has taken relevance to induce long-term tolerance, especially in the context of allogeneic stem cell transplantation.
Evelyn Katy Alvarez-Salazar (8656917)   +7 more
core   +1 more source

Neoantigen-Specific Cytotoxic TR1 CD4 T Cells Suppress Cancer Immunotherapy

open access: yes
CD4+ T cells can either enhance or inhibit tumour immunity. Although regulatory T cells have long been known to impede antitumour responses1-5, other CD4+ T cells have recently been implicated in inhibiting this response6,7.
Sultan, Hussein   +26 more
core   +1 more source

Primary Tr1 cells from metastatic melanoma eliminate tumor-promoting macrophages through granzyme B- and perforin-dependent mechanisms

open access: yes, 2017
In malignant melanoma, tumor-associated macrophages play multiple roles in promoting tumor growth, such as inducing the transformation of melanocytes under ultraviolet irradiation, increasing angiogenesis in melanomas, and suppressing antitumor immunity.
Hongjun Fu   +7 more
core   +1 more source

Adult liver stem cells in hepatic regeneration and cancer

open access: yes, 2015
An alternative source of livers for transplantation in patients with (genetic) liver diseases and liver failure is needed because liver donors are scarce. HPC-derived hepatocyte-like cells could be one of the options.
Nantasanti, Sathidpak   +2 more
core  

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