Results 81 to 90 of about 3,289 (220)
Ocular hypotension, actin stress fiber disruption and phagocytosis increase by RKI-1447, a Rho-kinase inhibitor [PDF]
, 2018 Objective: The Rho GTPase/Rho kinase pathway is an important target in glaucoma treatment. This study investigated the hypotensive effect of RKI-1447, a Rho kinase inhibitor developed for cancer treatment, in a porcine ex vivo pigmentary glaucoma model.
Dang, Yalong +5 more
core +1 more source
American Journal of Medical Genetics Part A, Volume 194, Issue 10, October 2024.Abstract Primary congenital glaucoma (PCG) is one of the leading causes of visual damage and blindness, severely affecting the quality of life of affected children. It is characterized by cupping of the optic disc and loss of ganglion cells due to elevated intraocular pressure. While most PCG patients exhibit epiphora, photophobia, and buphthalmos with
Oscar Francisco Chacon‐Camacho +13 more
wiley +1 more source
Clinical Ophthalmology, 2022 Mark J Gallardo,1 Mark F Pyfer,2 Steven D Vold,3 Steven R Sarkisian Jr,4 Anita Campbell,5 Inder Paul Singh,6 Brian Flowers,7 Kavita Dhamdhere8 On behalf of the GEMINI study group1El Paso Eye Surgeons, PA, El Paso, TX, USA; 2Northern Ophthalmic Associates,
Gallardo MJ +7 more
doaj
Surgical management of primary congenital glaucoma in egypt
Journal of the Egyptian Ophthalmological Society, 2016 Purpose To study primary congenital glaucoma characteristics and surgery in a University-based practice in Egypt. Patients and methods The present study was a retrospective chart review of 165 eyes of 112 children who presented and were operated upon ...
Nader H.L. Bayoumi
doaj +1 more source
Primary cilia signaling mediates intraocular pressure sensation [PDF]
, 2014 Lowe syndrome is a rare X-linked congenital disease that presents with congenital cataracts and glaucoma, as well as renal and cerebral dysfunction. OCRL, an inositol polyphosphate 5-phosphatase, is mutated in Lowe syndrome.
Cantor, Louis B. +13 more
core +2 more sources
The FASEB Journal, Volume 38, Issue 10, 31 May 2024.DDX58 variant‐induced IFN‐β regulates autophagy in TM cells via RSAD2 and influences IOP in atypical SMS. In healthy TM cell, RIG‐I does not recognize self‐dsRNA, thus preventing triggering downstream signaling. In TM cells of atypical SMS, SMS‐RIG‐I recognizes and continuously binds self‐dsRNA, leading to the activation of MAVs and downstream ...
Xinting Huang +5 more
wiley +1 more source
Clinical Ophthalmology, 2021 Mark F Pyfer,1 Mark Gallardo,2 Anita Campbell,3 Brian E Flowers,4 Jaime E Dickerson Jr,5,6 Alain Talla,5 Kavita Dhamdhere5,7 1Northern Ophthalmic Associates, Jenkintown, PA, USA; 2El Paso Eye Surgeons, PA, El Paso, TX, USA; 3Grene Vision Group, Wichita ...
Pyfer MF +6 more
doaj
ARC syndrome accompanied with glaucoma in one of two affected siblings
Pediatrics International, Volume 67, Issue 1, January/December 2025.
Takashi Okuno +4 more
wiley +1 more source
Trabeculotomy Augmented by Postoperative Topical Medications vs. Trabeculectomy Augmented by Mitomycin C [PDF]
, 2016 Purpose: To study the safety and hypotensive effect of trabeculotomy augmented by postoperative topical medical treatment in patients with open-angle glaucoma and to compare with trabeculectomy augmented by mitomycin ...
Kobayashi, Hiroshi
core +1 more source
Excimer Laser Trabeculotomy [PDF]
Ophthalmologica, 2008 ous fluid by producing 0.5-mm holes. There is no reference given to this observation, therefore it is not clear how this observation was determined. The article states that the laser fiber is 200 m. It is unclear how this would create 500m ostia. On page 286, an aiming beam is mentioned in the Surgical Technique section. However, unless the AIDA laser
openaire +1 more source