Results 1 to 10 of about 26,372 (185)

Pharmacological interventions enhance virus-free generation of TRAC-replaced CAR T cells

Molecular Therapy - Methods and Clinical Development, 2022
Chimeric antigen receptor (CAR) redirected T cells are potent therapeutic options against hematological malignancies. The current dominant manufacturing approach for CAR T cells depends on retroviral transduction.
Michael Schmueck-Henneresse, Maik Stein, Renata Stripecke   +2 more
exaly   +3 more sources

A TRAC-478-adjuvanted recombinant N1 neuraminidase influenza virus vaccine induces balanced and broadly protective immune responses [PDF]

npj Vaccines
Licensed influenza vaccines primarily target the variable hemagglutinin protein and provide inadequate cross-protection against mismatched or drifted viral strains.
Irene Hoxie, Kirill Vasilev, Jordan Clark, Hardik Amin, Garazi Peña Alzua, Disha Bhavsar, Eduard Puente-Massaguer, Karthik Siram, Kristopher Short, Rebekah Tee, David Burkhart, Jay T. Evans, Florian Krammer   +12 more
doaj   +2 more sources

Generation of Allogeneic CAR-T Circumvents Functional Deficits in Patient-Derived Autologous Product for Glioblastoma. [PDF]

Int J Cancer
Clinical trials of chimeric antigen receptor T‐cell (CAR‐T) therapies in glioblastoma have shown limited clinical benefits. Whether this may be explained by the basal quality of CAR‐T products, which are currently generated using patient, autologous T‐cells, has been little explored.
Salim SK, Shaikh MV, Wei J, Maich WT, Anand A, Tang OY, Subapanditha MK, Alizada Z, Suk Y, Singh M, Zhai K, Khanna A, Brakel B, Dimitrov V, Tabunshchyk Z, Chan K, Brown KR, Vora P, O'Rourke DM, Binder ZA, Venugopal C, Moffat J, Singh SK.   +22 more
europepmc   +2 more sources

The tracking and reducing alcohol consumption (TRAC) intervention for veterans living with HIV/AIDS: results from a pilot randomized waitlist-controlled trial [PDF]

Addiction Science & Clinical Practice
Background Veterans with HIV/AIDS (VWH) frequently report alcohol misuse, which can impact antiretroviral therapy (ART) adherence and lead to poorer clinical outcomes.
Carolyn Lauckner, Reuben Adatorwovor, Erica Taylor, Fidelis Sesenu, Tehquin Tanner, Alexis Whitmire, Vincent Marconi, Trace Kershaw, Nathan Hansen   +8 more
doaj   +2 more sources

Driving Force and Blossoming Analysis of a Composite Triangular Rollable and Collapsible (TRAC) Boom Used in Aerospace Technologies

Aerospace
Deployable and foldable tape-spring booms are widely used in aerospace technologies, especially for large-scale membrane structures. Semi-circular (STEM) and lenticular (CTM) boom cross-sections were invented for specific applications since these ...
Sicong Wang
exaly   +3 more sources

International Arbitration Faced with the Challenge of Economic Sanctions [PDF]

Majallah-i Huqūqī-i Biyn/al-milalī-i, 2023
The multiplication of economic sanctions has caused serious challenges for the users of international arbitration. Access to international arbitration and, more particularly, to institutional arbitration has been seriously affected by their ever-growing ...
مشکان مشکور
doaj   +1 more source

Role of consumer ethnocentrism on purchase intention toward foreign products: Evidence from data of Vietnamese consumers with Chinese products

Heliyon, 2023
This study aims to determine the influence of consumer ethnocentrism and general country image on Vietnamese consumers' perception of product origin and purchase intention toward Chinese goods.
Ngoc Ha Nguyen, Trung Kien Dao, Thanh Thuy Duong, Tuan Thanh Nguyen, Van Ky Nguyen, Thi Lanh Dao   +5 more
doaj   +1 more source

TRAC at 30: A Bibliometric Analysis of the TRAC Community

Theoretical Roman Archaeology Journal, 2021
As TRAC approaches another milestone anniversary there is much to celebrate - a successful conference, a large body of publications, and a thriving community.
Nicky Garland
doaj   +2 more sources

Association between electronic nicotine delivery systems (ENDS) device and E-liquid alterations and flavor use with clinical and EVALI-like symptoms

Preventive Medicine Reports, 2021
Studies reporting clinical symptoms related to electronic nicotine delivery systems (ENDS) usage, especially types of devices and e-liquids, are sparse.
Joy L. Hart, Thomas J. Payne, Allison Groom, Hy Tran, Kandi L. Walker, Anshula Kesh, Rose Marie Robertson, Thanh-Huyen T. Vu   +7 more
doaj   +1 more source

ویرایش ژنی هدفمند در سلول‌های T پرایمری انسان با استفاده از ریبونوکلئوپروتئین‌های CRISPR/Cas9 [PDF]

مجله دانشکده پزشکی اصفهان, 2021
مقدمه: ناک اوت ژنی سلول‌های T پرایمری با واسطه‌ی Clustered regularly interspaced short palindromic repeats/ CRISPR-associated protein 9 (CRISPR/Cas9) محدودیت‌های زیادی برای کاربردهای بالینی دارد. انتقال مستقیم پروتئین نوترکیب Cas9 و Guide RNA (gRNA)
doaj   +1 more source