Results 101 to 110 of about 26,372 (185)

Synergistic engineering of Casδ nuclease for robust genome editing

Journal of Integrative Plant Biology, Volume 68, Issue 9, Page 3231-3242, September 2026.
A hierarchical engineering strategy was used to enhance the editing activity of Casδ, yielding an optimized variant termed enCasδ. This variant enables robust genome editing in animal cells and plants, with overall editing performance comparable to that of SpCas9 and other Cas12 nucleases.
Fanghui Ge, Chenchen Peng, Yang Du, Ying Chen, Zilong Zhao, Meixia Yu, Huairu Feng, Yuyang Xie, Siwei Sun, Shengnan Liu, Beibei Xin, Haiming Zhao, Sen Wu, Chao Bian, Zhijia Yang, Jinsheng Lai, Jian Chen   +16 more
wiley   +1 more source

Fatigue and Cognitive Impairment in Adults With Primary Sclerosing Cholangitis: Results From Concept Elicitation Interviews

Liver International, Volume 46, Issue 9, September 2026.
ABSTRACT Background and Aims To understand the experience of fatigue and cognitive impairment in adults with symptomatic primary sclerosing cholangitis (PSC) as an essential first step towards developing PSC‐specific symptom measures. Methods Purposeful sampling was used to identify 17 symptomatic adults from the PSC Symptom Assessment Project who met ...
Donna M. Evon, Kaya Merkler, Laura Mkumba, Nicole Lucas, Lauren Wright, Joanne Hatchett, Rachel Gomel, Patrick J. Smith, Sasha Deutsch‐Link, Christopher L. Bowlus, Mark G. Swain, Bryce B. Reeve   +11 more
wiley   +1 more source

Writing Big in Plant Genomes: Advances, Challenges and Strategies for Targeted Large‐Fragment DNA Insertion

Plant, Cell &Environment, Volume 49, Issue 9, Page 6506-6520, September 2026.
ABSTRACT Precise genome editing has transformed plant biology and crop improvement by enabling targeted modification of endogenous loci. Beyond gene knockout and base editing, the site‐specific insertion of exogenous DNA, particularly large DNA fragments, has become a central goal for engineering complex traits, reconstructing metabolic pathways and ...
Fengfeng Zhang, Daqi Yan, Jiayi Hou, Dan Yang, Yan Xiong, Mingzhang Wen, Xiaoyue Zhu   +6 more
wiley   +1 more source

QUAN TRẮC VÀ ĐÁNH GIÁ XU HƯỚNG BIẾN ĐỘNG CHẤT LƯỢNG NƯỚC HẠ LƯU SÔNG CU ĐÊ, THÀNH PHỐ ĐÀ NẴNG

Tạp chí Khoa học Đại học Cần Thơ, 2014
Mục đích của bài báo này nhằm trình bày các kết quả phân tích xu hướng biến động chất lượng nước hạ lưu sông Cu Đê bằng phương pháp thống kê. Các thông số chất lượng nước được nghiên cứu tiến hành lấy mẫu, quan trắc bao gồm Nhiệt độ, hàm lượng oxy hòa ...
Nguyễn Minh Kỳ
doaj  

Artificial Intelligence in Xenotransplantation: A Prioritized Roadmap for Early Clinical Translation, Opportunities and Challenges

Xenotransplantation, Volume 33, Issue 5, September/October 2026.
ABSTRACT Xenotransplantation represents a potential solution to the persistent global organ shortage, yet its clinical application remains stalled by complex immunologic responses, coagulation dysregulation, species‐specific biology, and infectious risks.
Kasra Shirini, Zoe Hahn, Joseph M. Ladowski, Alexander Schulick, Saghar Babadi, Alexandre Loupy, Kazuhiko Yamada, Raphael P. H. Meier   +7 more
wiley   +1 more source

Study of MOX-fueled VVER-1000 pin cell using ν-TRAC with ENDF/B-VIII.0 library

Physics Open
This paper compares the ENDF/B-VIII.0 library for the MOX-fueled VVER-1000 pin cell benchmark with ENDF/B-VII.0 library using the ν-TRAC code and demonstrates the modeling capability of the code.
Anmol Singh, Usha Pal, R. Karthikeyan, V. Harikrishnan   +3 more
doaj   +1 more source

TRAC-PF1 choked-flow model [PDF]

, 1983
The two-phase, two-component choked-flow model implemented in the latest version of the Transient Reactor analysis Code (TRAC-PF1) was developed from first principles using the characteristic analysis approach. The subcooled choked-flow model in TRAC-PF1
Sahota, M.S., Lime, J.F.
core  

Terrorism Research & Analysis Consortium (TRAC).

Perspectives on Terrorism, 2012
Published online at < http://www.trackingterrorism.org/ > by the Beacham Group LLC. Priced from US $ 350.- upwards, depending on type of user (individual, organization, government)  Reviewed by Alex P ...
Alex P. Schmid
doaj  

Profils d’entrée et besoins différencies dans la formation à l’exposé oral en français universitaire professionnalisant : étude dans une grande école de commerce et de gestion

Akofena
Résumé : À partir des réponses de 192 étudiants de première année d’une école de commerce et de gestion, cet article interroge la valeur diagnostique de l’aisance initiale déclarée dans une formation à l’exposé oral en français.
Zouhir EL BOUCHIKHI
doaj   +1 more source

TRAC independent assessment for PWR analysis [PDF]

, 1983
LANL is developing the Transient Reactor Analysis Code (TRAC) for application to PWRs. Goal was to analyze large-break loss-of-coolant accidents (LOCAs), and the TRAC-P1A and TRAC-PD2 codes primarily addressed the large-break LOCA.
Knight, T. D.
core