Results 61 to 70 of about 15,334 (193)

Redox‐aktivierte Sonden für Hochkontrastige Live‐Bildgebung Postsynaptischer Neuronaler Gerüste

Angewandte Chemie, Volume 138, Issue 11, 9 March 2026.
Sylives sind modifizierte fluoreszierende Peptide für eine kontrastreiche Live‐Bildgebung inhibitorischer (Gephyrin) und exzitatorischer (PSD‐95) postsynaptischer Gerüststrukturen in nativen Neuronen. Eine saubere Markierung erfordert niedrige Sondenkonzentrationen im Nanomolarbereich, während die Aufnahme mikromolare Konzentrationen zellpenetrierender
Christiane Huhn, Clémence Mille, Sheng‐Yang Ho, Felix Lützenkirchen, Vladimir Khayenko, Melanie Hein, Christian Werner, Matthias Kneussel, Johannes W. Hell, Christian G. Specht, Hans M. Maric   +10 more
wiley   +1 more source

Schnelle RASER‐MRT

Angewandte Chemie, Volume 138, Issue 10, 2 March 2026.
Schnelle RASER‐MRT ermöglicht Bildgebung ohne RF‐Anregung. Stattdessen wird eine Populationsinversion der Kernspins durch SABRE‐Hyperpolarisation erzeugt, die eine Selbstanregung durch RASER ermöglicht. Wenn die gewünschte transversale Magnetisierung aufgebaut ist, wird herkömmliche EPI‐Kodierung ausgelöst, um das Bild aufzuzeichnen.
Sören Lehmkuhl, Simon Fleischer, Jing Yang, Eduard Y. Chekmenev, Thomas Theis, Stephan Appelt, Jan G. Korvink, Mazin Jouda   +7 more
wiley   +1 more source

Sử dụng phần mềm IATA để phân tích, đánh giá và nâng cao chất lượng câu hỏi trắc nghiệm khách quan trong chương hàm số lũy thừa, hàm số mũ, hàm số lôgarit

Tạp chí Khoa học Đại học Cần Thơ, 2018
Bài viết này trình bày tổng quan về Lý thuyết ứng đáp câu hỏi (IRT) cũng như giới thiệu sơ lược về cách cài đặt và sử dụng phần mềm IATA – một phần mềm dùng để phân tích, đánh giá câu hỏi trắc nghiệm khách quan (TNKQ) dựa trên nền tảng IRT.
Bùi Anh Kiệt, Bùi Nguyên Phương
doaj   +1 more source

Structure‐Guided Engineering of a Cas12i Nuclease Unlocks Near‐PAMless Genome Editing

Advanced Science, Volume 13, Issue 17, 23 March 2026.
CRISPR‐Cas nucleases are limited by PAM requirements, restricting genome accessibility. Structure‐guided engineering of the compact Cas12i nuclease SF01 produced three variants with near‐PAMless, enabling efficient editing at diverse 5'‐NNTN‐3' sites. These nucleases expand the editable portion of the human genome more than fourfold, enabling efficient
Qitong Chen, Hanlin Gou, Chao Xu, Sihan Wang, Huitao Zhang, Minglei Song, Mengge Wang, Xingkun Ji, Xiaofei Wei, Yuanyan Tan, Hehua Quan, Pengyu Luo, Hanyu Shou, Pengpeng Liu, Yafeng Liang, Jian‐Kang Zhu   +15 more
wiley   +1 more source

Cooperative Perception Message Transmission Control Scheme Based on Information Value [PDF]

Jisuanji gongcheng
Roadside Units (RSU) detect and sense the road environment to form a Cooperative Perception Message (CPM), and this CPM is transmitted from the RSU to vehicles on a road.
LIU Jianhang, ZHOU Xiang, LI Shibao, CUI Xuerong
doaj   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Genotype II Live-Attenuated ASFV Vaccine Strains Unable to Completely Protect Pigs against the Emerging Recombinant ASFV Genotype I/II Strain in Vietnam

Vaccines
Background: African swine fever virus (ASFV) continues to spread globally, causing severe economic losses to pig farmers. Vietnam licensed two live attenuated vaccines based on the ASFV strains ASFV-G-ΔI177L and ASFV-G-ΔMGF to control the ongoing ASF ...
Nguyen Van Diep, Nguyen Van Duc, Nguyen Thi Ngoc, Vu Xuan Dang, Tran Ngoc Tiep, Viet Dung Nguyen, Thi Tam Than, Dustin Maydaniuk, Kalhari Goonewardene, Aruna Ambagala, Van Phan Le   +10 more
doaj   +1 more source

Population and single‐cell analyses reveal immune cell‐specific expression profiles associated with Alzheimer's disease risk

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION Dysregulation of the peripheral immune system may increase Alzheimer's disease (AD) risk, but the underlying cell type‐specific mechanisms remain unclear. METHODS We conducted Mendelian randomization and colocalization analyses of 4489 genes using single‐cell expression quantitative trait locus data from unstimulated and ...
Joni V. Lindbohm, Martin Stražar, Hang‐Mao Lee, Orr Ashenberg, Nina Mars, Pyry N. Sipilä, Samuli Ripatti, Dan Graham, Mika Kivimäki, Ramnik J. Xavier   +9 more
wiley   +1 more source

Driving Force and Blossoming Analysis of a Composite Triangular Rollable and Collapsible (TRAC) Boom Used in Aerospace Technologies

Aerospace
Deployable and foldable tape-spring booms are widely used in aerospace technologies, especially for large-scale membrane structures. Semi-circular (STEM) and lenticular (CTM) boom cross-sections were invented for specific applications since these ...
Sicong Wang, Shuhong Xu, Lei Lu, Lining Sun   +3 more
doaj   +1 more source

Hybrid Energy Management for Electric Vehicles: Enhancing Battery Lifespan and Efficiency With Marine Predator Algorithm and Dynamic Floating Mechanism

Engineering Reports, Volume 8, Issue 3, March 2026.
An intelligent energy management system (IEMS) optimized by the MPA‐DFM approach dynamically regulates battery power using supercapacitor energy in hybrid electric vehicles. The proposed control strategy minimizes battery stress and power loss, extends lifetime, and ensures real‐time stability across transient and steady‐state driving conditions ...
Yassine Bouteraa, Mohammad Khishe
wiley   +1 more source