Results 1 to 10 of about 167,373 (137)

SARS-CoV-2 SUD2 and Nsp5 Conspire to Boost Apoptosis of Respiratory Epithelial Cells via an Augmented Interaction with the G-Quadruplex of BclII

mBio, 2023
The molecular mechanisms underlying how SUD2 recruits other proteins of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to exert its G-quadruplex (G4)-dependent pathogenic function is unknown.
Ying Li, Quanwei Yu, Ridong Huang, Hai Chen, Hequan Ren, Lingling Ma, Yang He, Weimin Li   +7 more
doaj   +1 more source

Effects of New Bayesian Penalized Likelihood Reconstruction Algorithm on Visualization and Quantification of Upper Abdominal Malignant Tumors in Clinical FDG PET/CT Examinations

Frontiers in Oncology, 2021
PurposeThis study evaluated the effects of new Bayesian penalized likelihood (BPL) reconstruction algorithm on visualization and quantification of upper abdominal malignant tumors in clinical FDG PET/CT examinations, comparing the results to those ...
Mitsuaki Tatsumi, Mitsuaki Tatsumi, Fumihiko Soeda, Takashi Kamiya, Junpei Ueda, Daisuke Katayama, Keiko Matsunaga, Tadashi Watabe, Hiroki Kato, Noriyuki Tomiyama   +9 more
doaj   +1 more source

Advantages of FBPA PET in evaluating early response of anti-PD-1 immunotherapy in B16F10 melanoma-bearing mice: Comparison to FDG PET

Frontiers in Oncology, 2022
PurposePET with L-4-borono-2-[18F] fluoro-phenylalanine (FBPA) was reported to be useful to differentiate malignant tumors and inflammation. Although immunotherapy with immune checkpoint inhibitors (ICIs) has been applied to cancer treatment recently ...
Mitsuaki Tatsumi, Fumihiko Soeda, Sadahiro Naka, Kenta Kurimoto, Kazuhiro Ooe, Hideyuki Fukui, Daisuke Katayama, Tadashi Watabe, Hiroki Kato, Noriyuki Tomiyama, Noriyuki Tomiyama   +10 more
doaj   +1 more source

Assessment of mediastinal tumors using SUVmax and volumetric parameters on FDG PET/CT [PDF]

Asia Oceania Journal of Nuclear Medicine and Biology, 2017
Objective(s): This study aimed to evaluate the role of pretreatment SUVmax and volumetric FDG positron emission tomography (PET) parameters in the differentiation between benign and malignant mediastinal tumors.
Takahiro Morita, Mitsuaki Tatsumi, Mana Ishibashi, Kayako Isohashi, Hiroki Kato, Osamu Honda, Eku Shimosegawa, Noriyuki Tomiyama, Jun Hatazawa   +8 more
doaj   +1 more source

Simplified Dynamic Phantom for Pediatric Renography: A Description of Instrument and Its Performance [PDF]

Asia Oceania Journal of Nuclear Medicine and Biology, 2019
Objective(s): Renography is used for the diagnostic evaluation of pediatric patients with a suspected obstruction of urinary tract or impaired renal function.
Takashi Kamiya, Tadashi Watabe, Koichi Fujino, Romanov Victor, Yoshiki Kawamura, Kayako Isohashi, Keiko Matsunaga, Mitsuaki Tatsumi, Hiroki Kato, Eku Shimosegawa, Jun Hatazawa   +10 more
doaj   +1 more source

One-pot and one-step automated radio-synthesis of [18F]AlF-FAPI-74 using a multi purpose synthesizer: a proof-of-concept experiment

EJNMMI Radiopharmacy and Chemistry, 2021
Background Fibroblast activation protein (FAP) is overexpressed in the stroma of many types of cancer. [18F]AlF-FAPI-74 is a positron emission tomography tracer with high selectivity for FAP, which has already shown high accumulation within human tumors ...
Sadahiro Naka, Tadashi Watabe, Thomas Lindner, Jens Cardinale, Kenta Kurimoto, Melissa Moore, Mitsuaki Tatsumi, Yuriko Mori, Eku Shimosegawa, Frank Valla, Hiroki Kato, Frederik L. Giesel   +11 more
doaj   +1 more source

Multi-Technique groundwater flow system analysis and dating of deep aquifers in Alessandria Basin (Piedmont - IT)

Acque Sotterranee, 2020
The aim of the study was to set up a protection system from pollution of the deep aquifer of the Alessandria basin, by redefining the recharge areas, focused on this portion of Piedmont territory, and therefore by creating some reserve areas of deep ...
Nicola Quaranta, Elena Cogo, Adriano Simoni, Elisa Sacchi, Mariachiara Caschetto, Massimo Marchesi   +5 more
doaj   +1 more source

Automated [18F]PSMA-1007 production by a single use cassette-type synthesizer for clinical examination

EJNMMI Radiopharmacy and Chemistry, 2020
Background [18F]PSMA-1007, a positron emission tomography (PET) tracer, specifically targets prostate-specific membrane antigen (PSMA), which is highly expressed in prostate cancer.
Sadahiro Naka, Tadashi Watabe, Kenta Kurimoto, Motohide Uemura, Fumihiko Soeda, Oliver C. Neels, Klaus Kopka, Mitsuaki Tatsumi, Hiroki Kato, Norio Nonomura, Eku Shimosegawa, Jens Cardinale, Frederik L. Giesel, Jun Hatazawa   +13 more
doaj   +1 more source

Oxygen-15 labeled CO2, O2, and CO PET in small animals: evaluation using a 3D-mode microPET scanner and impact of reconstruction algorithms

EJNMMI Research, 2017
Background Positron emission tomography (PET) studies using 15O-labeled CO2, O2, and CO have been used in humans to evaluate cerebral blood flow (CBF), the cerebral oxygen extraction fraction (OEF), and the cerebral metabolic rate of oxygen (CMRO2) and ...
Genki Horitsugi, Tadashi Watabe, Yasukazu Kanai, Hayato Ikeda, Hiroki Kato, Sadahiro Naka, Mana Ishibashi, Keiko Matsunaga, Kayako Isohashi, Eku Shimosegawa, Jun Hatazawa   +10 more
doaj   +1 more source

Evaluation of the distribution of spray deposits within a vine canopy from measurements on artificial targets and real leaves

OENO One, 2022
Understanding the distribution of intercepted spray deposits is important for the study of the dose-response relationship of spraying a targeted pathogen and for the optimisation of the spraying process.
Anice Cheraiet, Olivier Naud, Mathilde Carra, Sébastien Codis, James Taylor   +4 more
doaj   +1 more source