Results 91 to 100 of about 223,903 (331)

Antispasmodic and bronchorelaxant activities of Salsola imbricata are mediated through dual Ca+2 antagonistic and β-adrenergic agonistic effects

open access: yesPharmaceutical Biology, 2017
Context: Salsola imbricata Forssk. (Chenopodiaceae) has folkloric repute for the treatment of various gastrointestinal and respiratory ailments. Objective: The present study investigates spasmolytic and bronchorelaxant effects of S. imbricata.
Naveed Aslam, Khalid Hussain Janbaz
doaj   +1 more source

One-dimensional modelling of pulse wave propagation in human airway bifurcations in space-time variables [PDF]

open access: yes, 2009
Airflow in the respiratory system is complicated as it goes through various regions with different geometries and mechanical properties. Three-dimensional (3-D) simulations are typically limited to local areas of the system because of their high ...
Alastruey, J   +3 more
core  

Indole‐3‐Propionic Acid Improves Alveolar Development Impairment via Targeting VAMP8‐mediated SNAREs Complex Formation in Bronchopulmonary Dysplasia

open access: yesAdvanced Science, EarlyView.
This study aims to evaluate the impact of the tryptophan‐derived metabolite indole‐3‐propionic acid (IPA) on lung development and autophagic flux. IPA alleviates hyperoxia‐induced alveolar arrest by promoting autophagosome‐lysosome fusion via inhibition of VAMP8 phosphorylation, which is suggestive of a promising therapeutic target of BPD.
Beibei Wang   +14 more
wiley   +1 more source

Chronic toxicity of inhaled thymol in lungs and respiratory tracts in mouse model. [PDF]

open access: yes, 2019
Epinephrine HFA (Primatene® Mist) is a newly formulated asthma metered dose inhaler developed to replace the previous Primatene® Mist CFC. The formulation of Epinephrine HFA contains thymol, a substance recognized to be safe by the FDA.
Luo, Mary Z   +3 more
core   +2 more sources

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

open access: yesAdvanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li   +7 more
wiley   +1 more source

Effect of Methanol Extract of Althaea Root on Contractile Function of Rat’s Tracheal Smooth Muscle

open access: yesJournal of Medicinal Plants, 2012
Background: The sudden involuntary muscular contractions of the air ways is a very common disease in human societies. Study on medical plant extracts to affect contractile activity of the tracheal smooth muscle can be useful manner in control of ...
M Mousavy - Lordjani   +3 more
doaj  

Anatomical and Morphometric Study of the Trachea in Pied Kingfisher Birds ( Ceryle rudis ).

open access: yesKufa Journal for Veterinary Medical Sciences, 2016
The present study include eleven of the Pied Kingfisher (Ceryle rudis) birds from both sex, the weight and length of body were (98 ± 6.901gm), (32 ± 0.524 cm) respectively.
Nabeel Abd Murad Al-Mamoori
doaj   +1 more source

Rupestonic Acid of Artemisia Rupestris L. Extract Treats Pulmonary Fibrosis in COPD by Targeting TGF‐β1

open access: yesAdvanced Science, EarlyView.
RA of EEAR inhibits TGF‐β1 ubiquitination and changes conformation by target binding TGF‐β1, regulating TGF‐β1/Smad2/3 signaling pathway. Thus it down‐regulated downstream protein expression, inhibited EMT and collagen deposition of ECM, in order to EEAR preventing PF in COPD.
Lingfeng Peng   +6 more
wiley   +1 more source

Optimal branching asymmetry of hydrodynamic pulsatile trees

open access: yes, 2010
Most of the studies on optimal transport are done for steady state regime conditions. Yet, there exists numerous examples in living systems where supply tree networks have to deliver products in a limited time due to the pulsatile character of the flow ...
B. Sapoval   +9 more
core   +1 more source

An Open Receptor-Binding Cavity of Hemagglutinin-Esterase-Fusion Glycoprotein from Newly-Identified Influenza D Virus: Basis for Its Broad Cell Tropism. [PDF]

open access: yes, 2016
Influenza viruses cause seasonal flu each year and pandemics or epidemic sporadically, posing a major threat to public health. Recently, a new influenza D virus (IDV) was isolated from pigs and cattle. Here, we reveal that the IDV utilizes 9-O-acetylated
Chen, Xi   +8 more
core   +3 more sources

Home - About - Disclaimer - Privacy