Results 91 to 100 of about 66,108 (301)

A mouse model of post-stroke pneumonia induced by intra-tracheal inoculation with Streptococcus pneumoniae

, 2016
Background: Stroke-induced immunodeficiency increases the risk of infectious complications, which adversely affects neurological outcome. Among those, pneumonia affects as many as one third of stroke patients and is the main contributor to mortality in ...
Lasitschka, F, Dalpke, A, Veltkamp, R, Stegemann-Koniszewski, S, Bruder, D, Mracsko, E, Na, S-Y   +6 more
core   +1 more source

SDPR–STK38 axis controls the proliferation–differentiation balance in alveolar type II cells

Animal Models and Experimental Medicine, EarlyView.
The present study identifies SDPR as a pivotal regulator orchestrating the balance between proliferation and differentiation in alveolar type II (AT2) cells. In SDPR+/+ cells, SDPR binds to and inhibits STK38 activity, thereby sustaining GSK‐3β signaling functionality to promote cyclin D1 degradation and maintain cell cycle homeostasis.
Jie Wang, Xuepei Lei, Yiying Huang, Jiaming Tang, Guiying Shi, Hang Li, Lin Bai   +6 more
wiley   +1 more source

Chrysin alleviates pressure overload–induced myocardial remodeling through regulating the PI3K/AKT/NRF2 pathway–mediated oxidative stress response

Animal Models and Experimental Medicine, EarlyView.
In this study, we primarily simulated pathological myocardial remodeling induced by transverse aortic constriction surgery and found significant cardiac hypertrophy and fibrosis, characterized by deteriorated cardiac function. Oxidative stress response is considered as a pivotal pathological process, which contributes to inflammation and apoptosis of ...
Yijia Wang, Xing Feng, Shuhui Zhao, Yuchong Fu, Ao Zhang, Xiaofeng Shen, Bowen Yu, Yihao Wang, Jiahui Lin, Bing Zhang, Weiping Ji, Lianpin Wu, Xiaoling Guo   +12 more
wiley   +1 more source

64 MDCT 3D Assessment of Complex Congenital Heart and Bilateral Tracheal Bronchi: A Case Report

Journal of Health Science and Medical Research (JHSMR), 2015
The tracheal bronchus manifests a variety of tracheobronchial anomalies. Bilateral tracheal bronchi are rare. Anomalous tracheal bronchus is usually asymptomatic.
Supika Kritsaneepaiboon, Supaporn Roymanee   +1 more
doaj  

Effect of kidsolone on isolated rat′s tracheal smooth muscle

, 2015
Purpose: Prednisolone (Kidsolone) is an anti-inflammatory drug that is mainly used for patients with chronic obstructive airway diseases (COAD), such as asthma and chronic obstructive pulmonary diseases (COPD).
Chi-Chung Wu, Shao-Cheng Liu, Hsing-Won Wang   +2 more
core   +1 more source

A novel mouse model of chronic Pseudomonas aeruginosa infection inducing bronchiectasis‐like phenotype

Animal Models and Experimental Medicine, EarlyView.
This graphical abstract highlights a bronchiectasis mouse model driven by chronic Pseudomonas aeruginosa (CPA)‐loaded agar beads plus papain, which reproduces significant airway structural damage, inflammation, mucous overproduction, and functional impairment, providing a clinically relevant platform for studying disease mechanisms and evaluating ...
Heng Yang, Yang Liu, Yuqing Wang, Yuhua Wen, Yan Chen, Rui Fan, Jiayan Xu, Shunlian Hu, Hao Qian, Rui Jiang, Weijun Cao, Jinfu Xu   +11 more
wiley   +1 more source

Prevalence of upper respiratory diseases and associated factors in Colombian Creole horses

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
To determine the prevalence of diseases of the upper respiratory tract and associated factors in the Colombian Creole Horse Valley Aburrá in 2015, a random sampling of 15 farms in southern Aburrá Valley under different management conditions was performed.
C. Jaramillo, M.P. Arias Gutierrez
doaj   +1 more source

Tracheal diseases: endoscopic evaluation and treatment

Pediatric Medicine, 2019
Rigid bronchoscopy has historically been introduced more than 100 years ago and has successfully passed the test of time reaching present with renewed interest and usefulness. For long time it was mainly performed for therapeutic interventions of foreign bodies removal and dilation of stenosis.
Gonfiotti, Alessandro, Droghetti, Andrea, Voltolini, Luca, Muriana, Giovanni, Divisi, Duilio, Crisci, Roberto, Viggiano, Domenico   +6 more
openaire   +2 more sources

Surgical reconstruction for congenital tracheal malformation and pulmonary artery sling

, 2019
Background Congenital tracheal malformations are less common than congenital cardiac diseases and surgical repair of these anomalies is complex. We sought to examine the surgical treatment and outcomes in cases of tracheal anomalies presenting with or ...
Viet Dang Quang Nguyen, Quang Khanh Huynh, Huu Vinh Vu   +2 more
core   +1 more source

Spatial Cell Death and Oxidative Stress Dynamics in Gas Plasma‐Treated Tumor Tissues

Advanced NanoBiomed Research, EarlyView.
Schematic representation of the four experimental models to study tissue penetration and oxidation. Four tissue models were used. Human pancreatic cancer cells were grown on the chorioallantois membrane of chicken embryos and gas plasma‐treated in ovo, murine colorectal tumor tissue was gas plasma‐exposed ex vivo, murine squamous cell carcinoma cells ...
Anke Schmidt, Shahrzad Rokhsary, Linus Hübner, Lea Miebach, Sander Bekeschus   +4 more
wiley   +1 more source