Results 151 to 160 of about 98,344 (310)

Chronic, Environmentally Relevant PM2.5 Exposure Exacerbates Metabolic Dysfunction‐Associated Steatotic Liver Disease and Early‐Stage Renal Dysfunction in a Rodent Model

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT While epidemiological studies link fine particulate matter (PM2.5) exposure to metabolic dysfunction‐associated steatotic liver disease (MASLD) and renal dysfunction, a translational gap exists, as most animal models utilize acute, high‐dose exposures that poorly reflect chronic, moderate‐level human scenarios.
Yi‐Siao Chen, Hugo You‐Hsien Lin, Chien‐Tzu Lin, Si‐Hua Huang, Ming‐Lun Yeh, Ming‐Lung Yu, Jin‐Ching Lee, Yao‐Chi Chung, Wei‐Ming Li, Ching‐Chia Li, Shiu‐Feng Huang, Chia‐Hung Yen   +11 more
wiley   +1 more source

Upper Airway Obstruction due to Kaposi Sarcoma—Presenting Sign of HIV: Case Report and Review

The Laryngoscope, EarlyView.
This study presents a case of undiagnosed HIV presenting with Kaposi sarcoma (KS) of the head and neck with acute upper airway obstruction (UAO) and provides an updated scoping literature review to examine the patient characteristics, lesion characteristics, interventions, and outcomes of KS cases with UAO from the pharynx, larynx, and/or trachea.
Zachary A. Wykoff, Logan F. McColl, Robert A. Baiocchi, Matthew O. Old   +3 more
wiley   +1 more source

Acromegaly Presenting With Cricoarytenoid Joint Arthropathy

The Laryngoscope, EarlyView.
Excess growth hormone in acromegaly induces characteristic acral and soft tissue overgrowth (particularly in the face and hands), arthropathies, as well as cardiovascular and metabolic complications. Similar proliferative changes can occur in the larynx, where hypertrophy of the arytenoid and cricoid cartilages may impair vocal fold mobility.
Samantha Salvi Cruz, Riley Larkin, Ioan Lina, Alexander Gelbard   +3 more
wiley   +1 more source

MAPK14 and its associated lncRNAs are up-regulated in lung tumors

Scientific Reports
MAPK14 and its related lncRNAs have been found to take part in the pathogenesis of cancers. We analyzed expression of MAPK14 and three related lncRNAs, namely NORAD, HCG11 and POLR1HASP (ZNRD1ASP) in 42 pairs of lung tumors and their nearby normal ...
Shahab Shahgaldi, Bashdar Mahmud Hussen, Solat Eslami, Arda Kiani, Soudeh Ghafouri-Fard   +4 more
doaj   +1 more source

Recurrent Respiratory Papillomatosis Foundation Position Statement on the Management of Adults With RRP

The Laryngoscope, EarlyView.
ABSTRACT Objective With regulatory approval of HPV‐specific immunotherapy for recurrent respiratory papillomatosis (RRP) and growing experience with systemic bevacizumab, a management algorithm incorporating these medical treatments is warranted. Data Sources and Methods RRP Foundation (RRPF) Key Opinion Leaders offer a proposed management algorithm ...
Simon R. Best, Aaron D. Friedman, Clark A. Rosen, Robert T. Sataloff, Laura A. Matrka, H. Steven Sims, David E. Rosow, Nabil F. Saba, David G. Lott, Adam M. Klein, Ted Mau, Milan R. Amin, Kathryn A. Wikenheiser‐Brokamp, Scott M. Norberg, Kim McClellan, Geoffrey D. Young, Clint T. Allen, on behalf of the Recurrent Respiratory Papillomatosis Foundation   +17 more
wiley   +1 more source

Factors Affecting Outcomes in Anterior Cervical Spine Surgery

The Laryngoscope, EarlyView.
This retrospective cohort study examined perioperative complications after anterior cervical spine surgery (ACSS) in 3401 patients treated at a tertiary academic institution. Otolaryngologist co‐surgeons in revision and upper cervical spine (C1‐4) cases, and high‐volume spine surgeons (≥ 15 annual cases) were associated with lower complication rates ...
Nana‐Hawwa Abdul‐Rahman, Hansen Deng, Jonathan Goulazian, Cynthia McMahan, Peter C. Gerszten, Carl H. Snyderman   +5 more
wiley   +1 more source

The Patient Perspective of Living With Recurrent Respiratory Papillomatosis

The Laryngoscope, EarlyView.
This study was conducted to better understand the perspectives and real‐world impact of the disease burden on patients diagnosed with recurrent respiratory papillomatosis (RRP) and caregivers who experience the disease daily. RRP results in clinical, financial, and psychosocial burdens. Increased public awareness of human papillomavirus (HPV) infection
Sara I. Pai, Walter Ochieng, Nancy Hedlund, Amanda Martino, Neha Chohan, Mir Pawlak, Edith Morais, Kim McClellan   +7 more
wiley   +1 more source

Effects of Mesenchymal Stem Cell‐Derived Exosomes on Lung Inflammation in a Murine Aspiration Model

The Laryngoscope, EarlyView.
This study assessed the effect of intravenous MSC‐derived exosomes on inflammatory lung injury in a rat model of LPS aspiration. Compared with LPS alone, MSC exosome treatment reduced histologic lung injury overall (significant group effect p = 0.02; linear trend p = 0.006) and significantly lowered Tnf gene expression on qRT‐PCR (p < 0.05).
Nogah Nativ‐Zeltzer, Rumi Ueha, Johnathon D. Anderson, Yuval Nachalon, Denise M. Imai, Peter C. Belafsky   +5 more
wiley   +1 more source

[Tracheal strictures in the course of Wegener's disease].

Otolaryngologia polska = The Polish otolaryngology, 1998
Two cases of tracheal strictures in the course of Wegener's disease are described. One patient died two months after tracheotomy, the other was successfully treated only by megachemotherapy (cyclophosphamide and steroids).
W, Skrobisz, B, Rydzewski
openaire   +1 more source

Airway Involvement in Conradi–Hünermann–Happle Syndrome: A Novel Clinical Manifestation

The Laryngoscope, EarlyView.
We report the first documented case of airway involvement in Conradi–Hünermann–Happle syndrome (CDPX2), an X‐linked dominant form of chondrodysplasia punctata caused by pathogenic variants in EBP. A 2‐month‐old female with genetically confirmed CDPX2 developed severe subglottic stenosis and persistent respiratory distress requiring CPAP; cross ...
Enrique G. Villarreal, Jackie Chiang, Evan J. Propst, Nikolaus E. Wolter   +3 more
wiley   +1 more source