Results 51 to 60 of about 75,191 (308)

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

open access: yesAdvanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li   +7 more
wiley   +1 more source

COMPARISON OF SEVOFLURANE VERSUS PROPOFOL FOR TRACHEAL INTUBATION IN CHILDREN

open access: yesPakistan Armed Forces Medical Journal, 2021
Objective: To compare the quality of intubation and hemodynamic response in children undergoing endotracheal intubation facilitated with propofol versus sevoflurane. Study Design: Quasi-experimental study. Place and Duration of Study: Department of
Zulfiqar Ali   +5 more
doaj   +1 more source

Tracheal suctioning improves gas exchange but not hemodynamics in asphyxiated lambs with meconium aspiration. [PDF]

open access: yes, 2015
BackgroundCurrent neonatal resuscitation guidelines recommend tracheal suctioning of nonvigorous neonates born through meconium-stained amniotic fluid.MethodsWe evaluated the effect of tracheal suctioning at birth in 29 lambs with asphyxia induced by ...
Gugino, Sylvia F   +7 more
core  

HMGB2 Promotes Cardiomyocyte Proliferation and Heart Regeneration Through MTA2‐Driven Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
In contrast to the adult mammalian heart, which lacks regenerative capacity, the neonatal heart retains a transient regenerative capacity. In this study, high mobility group box 2 (HMGB2) is identified as a crucial protein driving heart regeneration based on comprehensive analyses using quantitative proteomics with tandem mass tag (TMT) labelling, RNA ...
Liu‐Hua Zhou   +17 more
wiley   +1 more source

Deciphering Neural Mechanisms Underlying Marmoset Dynamic Natural Behaviors Using a Miniaturized Wireless Large‐Scale Coverage Neural Recorder

open access: yesAdvanced Science, EarlyView.
This study introduces a miniaturized wireless neural recording system integrated with custom‐designed 120‐channel µECoG arrays, engineered for monitoring brain activities in freely behaving marmosets. The system can capture and characterize behavior‐specific neural signals, including drinking‐related activation, pre‐vocalization anticipatory responses,
Hongru Liu   +22 more
wiley   +1 more source

Orotracheal intubation in infants performed with a stylet versus without a stylet [PDF]

open access: yes, 2017
Background: Neonatal endotracheal intubation is a common and potentially life-saving intervention. It is a mandatory skill for neonatal trainees, but one that is difficult to master and maintain.
Davis, Peter G.   +7 more
core   +2 more sources

Engineered Multifunctional Hydrogel Delivering Novel CBX7 Inhibitor Modulates Cuproptosis Via Liquid–Liquid Phase Separation to Restore Cardiac Function in Aged Myocardial Infarction

open access: yesAdvanced Science, EarlyView.
An age‐adapted therapy pairs δ‐Amyrenone, a CBX7 inhibitor, with an alginate hydrogel (CSAδ) to rescue infarcted elderly hearts. CSAδ disrupts CBX7–ATP7A liquid–liquid phase separation, restores ATP7A trafficking and copper efflux, suppresses cuproptosis, supplies oxygen, scavenges ROS, promotes M2 polarization, supports angiogenesis, and enhances ...
Jun Liu   +11 more
wiley   +1 more source

Study and reflection on anesthesia for tracheobronchopathia osteochondroplastica

open access: yesJournal of International Medical Research, 2020
Tracheobronchopathia osteochondroplastica (TO) is a rare disease that may cause unexpected difficult intubation. There is no available consensus on the management of difficult intubation that is associated with TO.
Luping Huang   +3 more
doaj   +1 more source

Should the Glidescope video laryngoscope be used first line for all oral intubations or only in those with a difficult airway? A review of current literature [PDF]

open access: yes, 2018
The purpose of this study was to review literature that looked into the efficacy of the Glidescope video laryngoscope versus the Macintosh laryngoscope in oral endotracheal intubations.
Hormis, Anil, Russell, Terrie-Marie
core   +1 more source

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