Results 211 to 220 of about 395,430 (339)

Diagnosis and Treatment of Primary Tracheobronchial Tumors. [PDF]

open access: yesCancer Med
Shu C   +9 more
europepmc   +1 more source

Comprehensive Insights into Tracheoesophageal Fistula Pathophysiology, Diagnosis, Treatment, and Future Directions

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
Tracheoesophageal fistula (TEF), a pathological trachea‐esophagus connection, arises congenitally or from malignancy/radiotherapy/trauma, causing aspiration and malnutrition. Diagnosis utilizes imaging and endoscopy. Treatment ranges from endoscopic stenting to surgical repair and conservative management.
Gang Li   +10 more
wiley   +1 more source

Controlling Release Kinetics of an Adjuvant from a Depot Improves the Efficacy of Local Immunotherapy in Metastatic Cancer

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
We show that intratumoral release of an immunotherapy—CpG —can be tuned with molecular precision by complexing it to an elastin‐like polypeptide (ELP). Injecting ELP‐CpG and an excipient ELP into tumors drives thermally‐triggered phase separation into a micro‐scale “sponge” depot that releases CpG at rates depending on the ELP composition, which ...
Joshua J. Milligan   +16 more
wiley   +1 more source

Engineered Dual‐Function Antibody‐Like Proteins to Combat SARS‐CoV‐2‐Induced Immune Dysregulation and Inflammation

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
Engineered antibody‐like proteins block the SARS‐CoV‐2 spike protein from binding to host receptors and suppress immune overactivation through an MBL‐based scaffold. These dual‐function proteins effectively alleviate inflammation, complement activation, and lung injury, offering a promising therapeutic strategy against severe COVID‐19 and its ...
Yizhuo Wang   +7 more
wiley   +1 more source

Preliminary Study on Phonation Reconstruction Using Free Anterolateral Thigh and Sternohyoid Myocutaneous Flaps After Total Laryngectomy

open access: yesCancer Medicine, Volume 14, Issue 19, October 2025.
ABSTRACT Objective In this study, we evaluated and compared the outcomes of phonation reconstruction using free anterolateral thigh (ALT) and sternohyoid myocutaneous flaps in patients undergoing total laryngectomy for locally advanced laryngeal and hypopharyngeal cancers, providing insights into optimal reconstructive approaches.
Hongming Wei   +9 more
wiley   +1 more source

Strawberry Gingivitis as the Primary Sign of ANCA‐Negative Granulomatosis With Polyangiitis (GPA): A Case Report

open access: yesClinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Wegener's granulomatosis (WG) could be a lethal disease if not diagnosed and managed timely. Oral involvement is rare and often presents as gingival hyperplasia with a traditional “strawberry gingivitis” appearance. Dental practitioners may be the first ones to encounter WG and may be able to prevent disease progression like the present case ...
Samaneh Salari   +4 more
wiley   +1 more source

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