Results 61 to 70 of about 18,506 (308)

Macrophage–Derived Ferritin Exacerbates Silica‐Induced Pulmonary Fibrosis via PIK3R2‐Mediated Fibroblast Differentiation

Advanced Science, EarlyView.
This study identifies ferritin as a pivotal mediator of silica‐induced pulmonary fibrosis. Macrophage‐derived ferritin drives fibroblast‐to‐myofibroblast differentiation via the PIK3R2/SMAD pathway, while ferritin knockdown alleviates fibrosis. These findings define ferritin as both a biomarker and pathogenic driver, highlighting ferritin‐PIK3R2 ...
Liqun Wang, Xuxi Chen, Hongying Quan, Rui Qian, Shuyu Gong, Qiurong He, Ying Gao, Ajia Axi, Manyu Zhao, Qin Zhang, Ling Zhang, Lijun Peng, Xin Sun, Ben Zhang, Yuqin Yao   +14 more
wiley   +1 more source

Insight into the Burden of Malignant Respiratory Tumors and their Relationship with Smoking Rates and Lead Contamination in Mexico

Toxics, 2022
We aimed to report the results from the Global Burden of Disease Study 2019 related to respiratory malignant tumors (tracheal, bronchial, and lung) in Mexico.
Oliver Mendoza-Cano, Efrén Murillo-Zamora, Ángeles Catalina Ochoa-Martínez, Valeria Argentina Mendoza-Olivo, Mónica Ríos-Silva, Xóchitl Trujillo, Miguel Huerta, Jaime Alberto Bricio-Barrios, Verónica Benites-Godínez, Irma González-Curiel, Rebeca Yasmín Pérez-Rodríguez, Nadia Azenet Pelallo-Martínez, Agustín Lugo-Radillo   +12 more
doaj   +1 more source

Intramuscular hemangioma of the retropharyngeal space [PDF]

, 2007
Background. Intramuscular hemangioma (IMH) is a distinctive type of hemangioma occurring within skeletal muscle. Most IMH are located in the lower extremity, particularly in the muscles of the thigh. When present in the head and neck region, the masseter
Bacetić Dragoljub, Boričić Ivan, Brašanac Dimitrije, Mikić Anton, Stojšić Zorica, Tomanović Nada   +5 more
core   +1 more source

Inactivation Rap2a in Endothelial Cell Prevents Pulmonary Fibrosis by Regulating Immune Microenvironment Through MAP4K4‐VCAM1 Signaling

Advanced Science, EarlyView.
We identified the endothelial RAP2A as a regulator of inflammatory endothelial activation in experimental lung fibrosis and suggest that targeting RAP2A‐mediated signaling may represent a potential strategy to modulate endothelial–immune crosstalk during fibrotic lung injury.
Xiaolan Zheng, Peng Yue, Kaiyu Zhou, Guidong Gong, Yue Zhang, Sha Lin, Xu Liu, Yanjiang Zheng, Siyuan Jing, Junling Guo, Yan Qi, Bi‐Sen Ding, Yimin Hua, Yifei Li   +13 more
wiley   +1 more source

A case of primary mediastinal Ewing′s sarcoma /primitive neuroectodermal tumor presenting with initial compression of superior vena cava

Annals of Thoracic Medicine, 2013
Ewing′s sarcomas and peripheral primitive neuroectodermal tumors (ES/PNETs) are high grade malignant neoplasms. These malignancies are characterized by a chromosome 22 rearrangement, arise from bone or soft tissue, predominantly affect children and young
Alessia Reali, Gianluca Mortellaro, Simona Allis, Edoardo Trevisiol, Silvia Maria Anglesio, Sara Bartoncini, Maria Grazia Ruo Redda   +6 more
doaj   +1 more source

Paraganglioma of the thyroid gland: A case report [PDF]

, 2014
Introduction. Thyroid paraganglioma is a very rare malignant neuroendocrine tumor. Immunohistochemical features of thyroid paraganglioma are helpful for the diagnosis. Case report.
Filipović Aleksandar, Pejakov Ljubica, Vučković Ljiljana   +2 more
core   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Respiratory tract involvement in Rosai–Dorfman disease – A report of two distinct cases

Heliyon
Rosai-Dorfman Disease (RDD), a rare histiocytic disorder typically characterized by painless cervical lymphadenopathy, can occasionally present extranodal presentations.
Qun Zhang, Qing Cai, Linling Jin, Wenqiu Ding, Mei Su, Yi Zhu, Wangjian Zha, Jiwang Wang   +7 more
doaj   +1 more source

Tracheal surgery

Monaldi Archives for Chest Disease, 2016
Surgical resection and reconstruction of the trachea can be performed both for benign and malignant diseases. The main indications for surgery include inflammatory (generally post-intubation), congenital or post-traumatic stenoses, degenerative lesions ...
A. D'Andrilli, E.A. Rendina, F. Venuta
doaj   +1 more source

Macrophages promote epithelial proliferation following infectious and non-infectious lung injury through a Trefoil factor 2-dependent mechanism. [PDF]

, 2019
Coordinated efforts between macrophages and epithelia are considered essential for wound healing, but the macrophage-derived molecules responsible for repair are poorly defined.
Beers, Michael F, Cohen, Noam A, Herbert, De'Broski R, Hung, Li-Yin, Katzen, Jeremey, Krummel, Matthew F, Nieves, Wildaliz, Oniskey, Taylor K, Sen, Debasish, Urisman, Anatoly, Vaughan, Andrew E   +10 more
core   +1 more source