Results 61 to 70 of about 15,556 (236)

Chrysin alleviates pressure overload–induced myocardial remodeling through regulating the PI3K/AKT/NRF2 pathway–mediated oxidative stress response

Animal Models and Experimental Medicine, EarlyView.
In this study, we primarily simulated pathological myocardial remodeling induced by transverse aortic constriction surgery and found significant cardiac hypertrophy and fibrosis, characterized by deteriorated cardiac function. Oxidative stress response is considered as a pivotal pathological process, which contributes to inflammation and apoptosis of ...
Yijia Wang, Xing Feng, Shuhui Zhao, Yuchong Fu, Ao Zhang, Xiaofeng Shen, Bowen Yu, Yihao Wang, Jiahui Lin, Bing Zhang, Weiping Ji, Lianpin Wu, Xiaoling Guo   +12 more
wiley   +1 more source

Tracheal Tumors - Resections and Palliative Care

, 2017
Aim: The primary malignant neoplasms of the trachea and tracheal invasion of cancer, although rare, are serious causes of morbidity and mortality. The treatment of tracheal tumors generally includes interventional endoscopy, surgery, radiation therapy ...
Angelov, A., Bizyokov, S., Marinchev, V., Kirova, G., Minchev, T., Stoimenov, I., Manolov, E.   +6 more
core   +1 more source

Chronic Cough Caused by Adenoid Cystic Carcinoma

Respirology Case Reports
Tracheal tumours can develop as primary neoplasms or as extensions from adjacent organs such as the lungs or larynx. We present a case of a man diagnosed with adenoid cystic carcinoma of the trachea.
Yu‐Tzu Chien, Yung‐Chia Huang, Chia‐Hung Hsu   +2 more
doaj   +1 more source

A novel mouse model of chronic Pseudomonas aeruginosa infection inducing bronchiectasis‐like phenotype

Animal Models and Experimental Medicine, EarlyView.
This graphical abstract highlights a bronchiectasis mouse model driven by chronic Pseudomonas aeruginosa (CPA)‐loaded agar beads plus papain, which reproduces significant airway structural damage, inflammation, mucous overproduction, and functional impairment, providing a clinically relevant platform for studying disease mechanisms and evaluating ...
Heng Yang, Yang Liu, Yuqing Wang, Yuhua Wen, Yan Chen, Rui Fan, Jiayan Xu, Shunlian Hu, Hao Qian, Rui Jiang, Weijun Cao, Jinfu Xu   +11 more
wiley   +1 more source

Spatial Cell Death and Oxidative Stress Dynamics in Gas Plasma‐Treated Tumor Tissues

Advanced NanoBiomed Research, EarlyView.
Schematic representation of the four experimental models to study tissue penetration and oxidation. Four tissue models were used. Human pancreatic cancer cells were grown on the chorioallantois membrane of chicken embryos and gas plasma‐treated in ovo, murine colorectal tumor tissue was gas plasma‐exposed ex vivo, murine squamous cell carcinoma cells ...
Anke Schmidt, Shahrzad Rokhsary, Linus Hübner, Lea Miebach, Sander Bekeschus   +4 more
wiley   +1 more source

The incidence of mTOR marker in tracheal adenoid cystic carcinoma by immunohistochemical staining

, 2020
Introduction: There is an association between the activation of mammalian target of rapamycin (mTOR) signaling and aggressive tumor growth in multiple forms of cancer, including adenoid cystic carcinoma (ACC).
Sadegh, Abdolreza; Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Taghavi, Kimia; Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Abedini, Atefeh; Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Kiani, Arda; Tracheal Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Pourabdollah Toutkaboni, Mihan; Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Farahani, Mehrdad; Department of Interventional Pulmonology, Tracheal Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Sadr, Makan; Virology Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran   +6 more
core   +3 more sources

Nanophotonic Biosensors and the Paradigm of Trans‐Scale Autonomous Bio‐Integrated Diagnostics for Addressing Health Complexities

Electron, EarlyView.
Physics‐driven advances in optical nanobiosensors for rapid, miniaturized, and point‐of‐care diagnostics for next‐generation decentralized and personalized healthcare based on sensor intelligence. ABSTRACT Public health emergencies and the escalating burden of chronic diseases necessitate a paradigm shift from centralized laboratory testing to rapid ...
Vishal Chaudhary, Harsh Sable, Sonu Sonu, Lakshita Phor, Reddicherla Umapathi, Pradeep Bhadola   +5 more
wiley   +1 more source

Management of Radiodermatitis in Patients With Head and Neck Cancer Undergoing Radiotherapy: A Scoping Review

Health Care Science, EarlyView.
The data obtained through this review highlight the lack of global consensus among radiotherapy centers on the best topical treatment for radiodermatitis. It indicates that the choice of treatment depends on professional judgment due to the absence of standardized guidelines, pointing to the need for more robust scientific research to develop effective
Tâmara Taynah Medeiros da Silva, Louise Constancia de Melo Alves Silva, Thatiane Evelyn de Lima Fernandes, Karena Cristina da Silva Leal, Thaís Brunna Maurício Pinheiro, Guilherme Moises Alves Fernandes, Kátia Regina Barros Ribeiro, Daniele Vieira Dantas, Rodrigo Assis Neves Dantas   +8 more
wiley   +1 more source

Secondary or Second Primary Endotracheal Cancer after Surgery for Primary Lung Cancer: Case Series and Review of the Literature

Chinese Journal of Lung Cancer, 2023
Background and objective The clinical feature, treatment and outcomes of the patients with endotracheal cancer after radical surgery for primary lung cancer are unclear.
Wei HUANG, Peixin TAN, Zhongbiao XU
doaj   +1 more source

Robotic‐Assisted Extended Sistrunk Approach (RESA) for Salvage Surgery After Head and Neck Irradiation

Head &Neck, EarlyView.
ABSTRACT Background The robotic‐assisted extended “Sistrunk” approach (RESA) is a minimally invasive technique providing access to hypopharyngeal and laryngeal structures via a submental incision and vallecular pharyngotomy, bypassing the base of tongue.
Bartosz Wojtera, Avinash Beharry, Karma Lambercy, Pascaline Dübi, Jelena Todic, Christian Simon   +5 more
wiley   +1 more source