Results 101 to 110 of about 51,443 (263)

Lung V5 and Planning Target Volume/Lung Volume Ratio as Independent Risk Factors for ≥Grade 2 Radiation Pneumonitis after Moderately Hypofractionated Radiotherapy: A Retrospective Study

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Lung V5 and the planning target volume/lung volume ratio were identified as independent dosimetric risk factors for clinically significant radiation pneumonitis following moderately hypofractionated radiotherapy for lung cancer. Maintaining V5 < 35% may help mitigate this risk in clinical practice.
YuanYou Yang, FengXia Luo, Chao Wang, Gang Ren   +3 more
wiley   +1 more source

Resolving Endoplasmic Reticulum‐Protein Misfolding Restores Corticosteroid Sensitivity in Experimental Models of Severe Asthma

Allergy, EarlyView.
This study investigates the role of ER stress in steroid resistance in severe asthma. Results from advanced 3D models of human bronchial epithelial cells, steroid‐resistant severe asthma mouse models, and human severe asthma sputum samples show that treatment with ICS in combination with the ER stress inhibitor 4‐PBA significantly enhances steroid ...
Prabuddha S. Pathinayake, Alexandra C. Brown, Nikhil T. Awatade, Philip M. Hansbro, Katherine J. Baines, Richard Y. Kim, Nathan W. Bartlett, Jay C. Horvat, Peter A. B. Wark   +8 more
wiley   +1 more source

Consent for anaesthesia: guidelines from the Association of Anaesthetists

Anaesthesia, EarlyView.
Summary Introduction Guidelines on consent for anaesthesia were first issued by the Association of Anaesthetists in 1999 and last revised in 2017. These new guidelines respond to the changing ethical, legal and clinical landscape in which anaesthetists practice. Since 2017, the Montgomery judgment has changed medical consent practice.
Andrew McLeod, David Bogod, James Brooks, Michael Devlin, Natalie Joseph‐Williams, Rehana Iqbal, Nadine Montgomery‐Allam, Felicity Plaat, Alex Ruck Keene, Cliff Shelton, Vinnie Sodhi, Michael Swart, Emma Wain, Hugo Wellesley, Jenny Westaway   +14 more
wiley   +1 more source

Giving Voice to Head and Neck Cancer Survivors: A Qualitative Investigation Into the Utility of Peer Support

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Head and neck cancer (HNC) survivors often experience significant physical and psychological challenges posttreatment, including functional impairments and social isolation. Peer support programs, where survivors share experiences and offer mutual support, can improve emotional well‐being, reduce isolation, and offer practical ...
Jevan Cevik, Amin Esmailian, Marcel Chua, Oliver Miles, Nelson Low   +4 more
wiley   +1 more source

Risk Factors for Complications Following Paediatric Neuromuscular and Syndromic Scoliosis Correction Surgery: A Systematic Review

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Paediatric neuromuscular and syndromic scoliosis patients have multiple medical comorbidities that increase the risk of postoperative complications. There is a lack of consistent literature assessing the specific risk factors for complications following scoliosis correction surgery in this high‐risk cohort.
Mai Pham, Mia A. Percival, Moya Vandeleur, Giuliana Antolovich, Kris Lundine   +4 more
wiley   +1 more source

Post‐Market Analysis of the Xenios Console With the Xlung Tubing Kit 230 for Extracorporeal Membrane Oxygenation After Cardiac Surgery

Artificial Organs, EarlyView.
This study is a comprehensive post‐market analysis of the Xenios console and XLung kit 230 preconfigured ECMO tubing set in post‐cardiotomy applications. The performance of this device was evaluated and demonstrated in all key clinical areas, with an adequate safety profile.
Luca Conci, Anne‐Kristin Schaefer, Thomas Schlöglhofer, Emilio Osorio‐Jaramillo, Amila Kahrovic, Alvaro Perazzo, Marcus Granegger, Daniel Zimpfer, Dominik Wiedemann, Julia Riebandt   +9 more
wiley   +1 more source

Therapeutic potential of a Bax inhibitor‐1/TMBIM6 antagonist (BIA) and its analogues in Aspergillus fumigatus‐induced asthma via dual targeting of AKT and epithelial‐derived inflammatory cytokines

British Journal of Pharmacology, EarlyView.
Background and Purpose Aspergillus fumigatus (A. fumigatus) exposure causes of severe allergic asthma, characterized by airway inflammation and epithelial dysfunction. TMBIM6 (Bax inhibitor‐1) has been implicated in airway epithelial stress responses and AKT signalling.
Young‐Jin Yu, Ahsan Ullah, Jisun Kim, Mehedi Hasan Bappi, Yerim Heo, Jin Hee Ahn, Hyun‐Kyoung Kim, Han‐Jung Chae   +7 more
wiley   +1 more source

Outcomes of children and young people with cerebral palsy receiving long‐term respiratory support: A systematic review

Developmental Medicine &Child Neurology, EarlyView.
Outcomes of children with cerebral palsy receiving long‐term respiratory support. Abstract Aim To systematically review the current knowledge gap in, and impact of, long‐term respiratory support in children and young people (CYP) with cerebral palsy (CP). Method We searched six databases from inception until 30th January 2025.
Rajkumar Dhandayuthapani, Alasdair Campbell, Catherine M McDougall, Florian Gahleitner, Steve Cunningham, Don S Urquhart   +5 more
wiley   +1 more source

Patient and Carer Participation in Reporting Patient Safety Incidents During Hospital Admission: A Scoping Review

Journal of Advanced Nursing, EarlyView.
ABSTRACT Background More than one in 10 patients experience harm in hospital, and patients with communication support needs are at higher risk. Patients and their carers are well‐placed to provide insights into patient safety incidents that may result in harm, which is essential to improving patient safety in hospitals.
Rebecca Sullivan, Tanya Ramadan, Shu En Lee, Robyn O'Halloran   +3 more
wiley   +1 more source

Being Wardable: Patient, Family and Staff Member Views of the Otherness of Critical Care Survivors in a Ward Setting

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aims Discharge from an intensive care unit (ICU) to the ward has long been recognised as a difficult and dangerous time for patients. This study aims to explore the experiences of patients, family members and staff of ongoing care following discharge from ICU to the ward.
Sarah Vollam, Melanie Gager, Hilary Thomas, Peter Watkinson, Natalie Pattison   +4 more
wiley   +1 more source