Results 11 to 20 of about 29,711 (189)

Cost-effectiveness of adding measurement of Chlamydia trachomatis infection and serology to trachoma prevalence surveys in Tanzania and Mozambique. [PDF]

PLoS Neglected Tropical Diseases
BackgroundAccurate methods to measure trachoma prevalence are critical to monitor progress and guide mass drug administration as countries near elimination.
Emily C Decker, Molly W Adams, William E Oswald, Rebecca M Flueckiger, Jeremiah M Ngondi, Mawo Fall, Ezgi E Yilmaz, Lisa C Brooks, George Kabona, Henis Mior Sitoe, Mabula Kasubi, Tamimo Momade, Thomas M Lietman, Thuy Doan, Rachel D Stelmach   +14 more
doaj   +2 more sources

Chlamydia trachomatis from Australian Aboriginal people with trachoma are polyphyletic composed of multiple distinctive lineages [PDF]

Nature Communications, 2016
Chlamydia trachomatis isolates causing a blinding disease (trachoma) form a single lineage that is different from the lineages causing urogenital infections. Here, Andersson et al.
Patiyan Andersson, Simon R. Harris, Helena M. B. Seth Smith, James Hadfield, Colette O’Neill, Lesley T. Cutcliffe, Fiona P. Douglas, L. Valerie Asche, John D. Mathews, Susan I. Hutton, Derek S. Sarovich, Steven Y. C. Tong, Ian N. Clarke, Nicholas R. Thomson, Philip M. Giffard   +14 more
doaj   +2 more sources

Active Trachoma Cases in the Solomon Islands Have Varied Polymicrobial Community Structures but Do Not Associate with Individual Non-Chlamydial Pathogens of the Eye [PDF]

Frontiers in Medicine, 2018
BackgroundSeveral non-chlamydial microbial pathogens are associated with clinical signs of active trachoma in trachoma-endemic communities with a low prevalence of ocular Chlamydia trachomatis (Ct) infection.
Robert M. R. Butcher, Oliver Sokana, Kelvin Jack, Eric Kalae, Leslie Sui, Charles Russell, Joanna Houghton, Christine Palmer, Martin J. Holland, Richard T. Le Mesurier, Anthony W. Solomon, David C. W. Mabey, Chrissy h. Roberts   +12 more
doaj   +5 more sources

Global, Regional, and National Burden of Trachoma: Cross-Country Inequalities, 1990–2021, with Projections to 2040 [PDF]

Ophthalmology and Therapy
Introduction In this work, we aim to evaluate the trends and cross-country inequalities of the global trachoma burden from 1990 to 2021 and to project its burden to 2040. Methods This study was a systematic analysis of the Global Burden of Diseases Study
Yang Meng, Furong Li, Shun Zeng, Chaoqun Liang, Wei Chi   +4 more
doaj   +2 more sources

Multilevel Analysis of Trachomatous Trichiasis and Corneal Opacity in Nigeria : The Role of Environmental and Climatic Risk Factors on the Distribution of Disease. [PDF]

, 2015
Funding: Jennifer L Smith was supported by the International Trachoma Initiative through a grant from the Bill and Melinda Gates Foundation. Anthony Solomon is a Wellcome Trust Intermediate Clinical Fellow (098521).
Gilbert, Clare, Kyari, Fatima, Rabiu, Mansur M., Sivasubramaniam, Selvaraj, Smith, Jennifer L, Solomon, Anthony W.   +5 more
core   +20 more sources

A Randomised Trial of Three Face-Washing Methods for the Removal of Chlamydia trachomatis From the Faces of Children With Severe Active Trachoma. [PDF]

Trop Med Int Health
ABSTRACT Objectives A three‐arm, open, parallel‐group randomised trial compared three face‐washing methods for cleaning Chlamydia trachomatis from the faces of children with severe active trachoma. The impact of face‐washing on Chlamydia trachomatis on the hands of children and their caregivers and Chlamydia trachomatis duration on faces and hands were
Greenland K, Butcher R, Etu ES, Abebe W, Bekele M, Dumessa G, Addisie YS, Ariya AT, Solomon AW, Czerniewska A, Macleod D, Last A, Abdurahman OS, Burton MJ, Abashawl A, Alemayehu W.   +15 more
europepmc   +2 more sources

Hidden in Plain Sight: The Enduring Challenge of Neglected Tropical Diseases in Khartoum State, Sudan. [PDF]

J Trop Med
Background Neglected tropical diseases (NTDs) disproportionately affect impoverished populations in tropical regions. Despite their significant health burden, data on NTD prevalence and distribution are limited in many areas, including Khartoum State, Sudan.
Rahamtalla BM.
europepmc   +2 more sources

Surgical output within the Fast Track Initiative against trachoma in Amhara region, Ethiopia

Journal of Infection in Developing Countries, 2022
Introduction: Trachomatous trichiasis (TT) is the advanced stage of trachoma where lashes touch the globe of the eye causing permanent damage. Without eyelid surgery, TT can lead to irreversible blindness.
Begashaw Hailemariam, Eshetu Sata, Mengesha Halefom, Andrew R Deathe, Mulat Zerihun, Kimberly A Jensen, E Kelly Callahan, Melkamu Beyene, Wim Adriaensen, Philip Owiti, Mbazi Senkoro, Maria Zolfo, Scott D Nash   +12 more
doaj   +1 more source

Optimizing cluster survey designs for estimating trachomatous inflammation–follicular within trachoma control programs

International Journal of Infectious Diseases, 2022
: Objectives: The World Health Organization recommends mass drug administration (MDA) with azithromycin to eliminate trachoma as a public health problem. MDA decisions are based on prevalence estimates from two-stage cluster surveys.
Julia W. Gallini, Eshetu Sata, Mulat Zerihun, Berhanu Melak, Mahteme Haile, Taye Zeru, Demelash Gessese, Zebene Ayele, Zerihun Tadesse, E. Kelly Callahan, Scott D. Nash, Paul S. Weiss   +11 more
doaj   +1 more source

Longitudinal Analysis of Antibody Responses to Trachoma Antigens Before and After Mass Drug Administration. [PDF]

, 2014
Blinding trachoma, caused by the bacteria Chlamydia trachomatis, is a neglected tropical disease targeted for elimination by 2020. A major component of the elimination strategy is mass drug administration (MDA) with azithromycin.
Dize, Laura, Gaydos, Charlotte, Goodhew, Erica Brook, Lammie, Patrick J, Martin, Diana L, Mkocha, Harran, Morgan, Sheri Maria, Munoz, Beatriz, Switzer, Andrew J, West, Sheila K, Wiegand, Ryan E   +10 more
core   +8 more sources