Results 41 to 50 of about 691,470 (246)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

PERSPECTIVES OF UKRAINIAN RAILWAY TOURISM DEVELOPMENT ON NARROW-GAUGE LINES OF ZAKARPATTIA

Nauka ta progres transportu, 2015
Purpose.The purpose of the paper is: (1) the definition of perspectives development of Ukrainian railway tourism on the narrow gauge lines of Zakarpattia; 2) technical condition analysis of Borzhava narrow gauge railway for the project to restore the ...
V. G. Kuznetsov, P. O. Pshinko, I. V. Klimenko, A. V. Gumenyuk, S. M. Zahorulko   +4 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Development of switching and adjustment devices for switch rails and proposal of a point of turnout to reduce maintenance labour

Nihon Kikai Gakkai ronbunshu
This study aims to develop switching and adjustment devices for switch rails, proposing a point of turnout that contributes to reduced maintenance efforts.
Shingo TAMAGAWA, Masashi UEDA, Shintaro YASUDA, Akito HOSOMI   +3 more
doaj   +1 more source

Track Fastener Defect Detection Model Based on Improved YOLOv5s

Sensors, 2023
Defect detection of track fasteners is a prerequisite for safe and reliable railroad operation. The traditional manual visual inspection method has been unable to meet the growing demand for railroad network inspection in China.
Xue Li, Quan Wang, Xinwen Yang, Kaiyun Wang, Hongbing Zhang   +4 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Willingness to repeat discharge on day of surgery after hip and knee arthroplasty

Bone & Joint Open
Aims: The limited documentation on patients’ perspectives on undergoing discharge on the day of surgery impedes its adoption as a standard of care. Hence, the aim of this study was to investigate whether patients were willing to repeat being discharged ...
Oddrún Danielsen, Kirill Gromov, Claus Varnum, Thomas H. Jakobsen, Mikkel R. Andersen, Manuel J. Bieder, Christoffer C. Jørgensen, Henrik Kehlet, Martin Lindberg-Larsen   +8 more
doaj   +1 more source

Integrated sensing and communication based outdoor multi-target detection, tracking, and localization in practical 5G Networks

Intelligent and Converged Networks, 2023
The 6th generation (6G) wireless networks will likely to support a variety of capabilities beyond communication, such as sensing and localization, through the use of communication networks empowered by advanced technologies.
Ruiqi Liu, Mengnan Jian, Dawei Chen, Xu Lin, Yichao Cheng, Wei Cheng, Shijun Chen   +6 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Feasibility of a prospective multicenter observational study—is diabetes a risk factor in ERAS joint arthroplasty?

Pilot and Feasibility Studies
Background Diabetes mellitus is a surgical risk factor, yet perioperative diabetes management remains debated, with inconsistent guidelines and limited consideration on the implementation of “enhanced recovery after surgery” (ERAS) programs.
Luma Mahmoud Issa, Christoffer Calov Jørgensen, Sten Madsbad, Martin Lindberg-Larsen, Claus Varnum, Thomas Jakobsen, Mikkel Rathsach Andersen, Manuel Josef Bieder, Søren Overgaard, Torben Bæk Hansen, Kirill Gromov, Henrik Kehlet   +11 more
doaj   +1 more source