Results 121 to 130 of about 158,302 (297)
Advanced Science, EarlyView.We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang +10 more
wiley +1 more source
Advanced Science, EarlyView.Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance +17 more
wiley +1 more source
THE TRACKED VEHICLE MOTION MATHEMATICAL MODEL BASED ON GIBBS-APPELL EQUATIONS
Sučasnì Informacìjnì Tehnologìï u Sferì Bezpeki ta Oboroni, 2015 This article is dedicated to the study of the curvilinear motion of tracked vehicles on the plane. Based on the Gibbs-Appell equations the mathematical model of the tracked vehicle on the two-dimensional surface has been formulated as a mechanical system
Andrii V. Rudyi, Denys V. Rudavskyi
doaj
Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53
Advanced Science, EarlyView.NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore +20 more
wiley +1 more source
Jixie chuandong, 2007 Due to the limit of the static strength theory designed in tracked vehicle,it can’t reflect the dynamic loads suffered by the main part,so it is difficulty to analysis the reliability and remained life prediction,in some degree it affect the performance ...
薛景波 +3 more
doaj
A Slip-Based Model Predictive Control Approach for Trajectory Following of Unmanned Tracked Vehicles
MachinesIn the field of tracked vehicle dynamics, studies show that vertical loads are concentrated under road wheels on firm road conditions, allowing slip-based models of tracked vehicles to be designed similar to wheeled vehicle models.
Ismail Gocer +1 more
doaj +1 more source
Video Guidance Sensors Using Remotely Activated Targets [PDF]
Four updated video guidance sensor (VGS) systems have been proposed. As described in a previous NASA Tech Briefs article, a VGS system is an optoelectronic system that provides guidance for automated docking of two vehicles.
Book, Michael L. +2 more
core +1 more source
Advanced Science, EarlyView.Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley +1 more source
VehiclesThe primary objective of this research is to address the existing gap about the use of a path-planning algorithm that will reduce energy consumption in off-road applications of tracked electric vehicles.
Taha Taner İnal +4 more
doaj +1 more source
Advanced Science, EarlyView.Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang +10 more
wiley +1 more source