Results 51 to 60 of about 1,722,613 (299)

Preliminary assessment of the therapeutic potential of staphylococcal enterotoxin-like W via biological activity and TCR binding sites analysis

Virulence
Staphylococcal enterotoxin-like W (SElW) is a novel, widely prevalent enterotoxin-like protein that functions as a classical staphylococcal superantigen (SAg) and has been shown to exacerbate infections caused by the S.
Yuhua Yang, Xiaoyue Wei, Fanliang Meng, Yanan Gong, Yahui Guo, Lijin Long, Jiaming Fan, Yakun Zhao, Wanting Wang, Di Xiao, Lei Wang, Maojun Zhang, Dongliang Hu, Jianzhong Zhang, Xiaomei Yan   +14 more
doaj   +1 more source

Guaranteed Cost Tracking for Uncertain Coupled Multi-agent Systems Using Consensus over a Directed Graph [PDF]

, 2013
This paper considers the leader-follower control problem for a linear multi-agent system with directed communication topology and linear nonidentical uncertain coupling subject to integral quadratic constraints (IQCs).
Cheng, Yi, Ugrinovskii, V., Wen, Guanghui   +2 more
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Health impacts of an extreme dust event: a case and risk assessment study on airborne bacteria in Beijing, China

Environmental Sciences Europe
Dust events are concerning due to their potential to cause environmental pollution and health issues by carrying numerous particles from various regions. However, the risks of airborne bacteria from dust have not yet been thoroughly investigated.
Yueyun Luo, Qiao Yao, Pei Ding, Min Hou, Fuchang Deng, Youbin Wang, Cheng Ding, Xia Li, Duochun Wang, Zongke Sun, Song Tang, Yixin Mao, Xiaoyuan Yao   +12 more
doaj   +1 more source

Morphological, lytic, and genetic characteristics of three Brucella phages isolated from Inner Mongolia Autonomous Region

Frontiers in Microbiology
This study comprehensively examined three Brucella phages (A1, NMY-1, and NMY-2) isolated from Inner Mongolia Autonomous Region. Electron microscopy classified them as short-tailed phages.
Yu Zhang, Yu Zhang, Dongri Piao, Qingqing Xu, Yu Fan, Hongyan Zhao, Kun Li, Guozhong Tian, Kuo Han, Hai Jiang   +9 more
doaj   +1 more source

A Trip to the Moon: Personalized Animated Movies for Self-reflection

, 2018
Self-tracking physiological and psychological data poses the challenge of presentation and interpretation. Insightful narratives for self-tracking data can motivate the user towards constructive self-reflection.
Bentley Todd, Braun Virginia, Freytag Gustav, Kihlstrom John F, Lancaster Kurt, Lancaster Kurt, Van Breemen AJN   +6 more
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Dengue situation in Chinese mainland, 2023

BMC Public Health
Background Dengue fever outbreaks have occurred in Chinese mainland in recent years, especially in 2014 and 2019. In 2023, following the Corona Virus Disease 2019 pandemic, dengue fever has exhibited some new trends and characteristics.
Yujuan Yue, Xinchang Lun, Chunchun Zhao, Xiaobo Liu, Ning Zhao, Yuhong Guo, Xiuping Song, Liang Lu, Dongsheng Ren   +8 more
doaj   +1 more source

Discrete Adaptive Second Order Sliding Mode Controller Design with Application to Automotive Control Systems with Model Uncertainties

, 2017
Sliding mode control (SMC) is a robust and computationally efficient solution for tracking control problems of highly nonlinear systems with a great deal of uncertainty.
Amini, Mohammad Reza, Hedrick, J. Karl, Pan, Selina, Shahbakhti, Mahdi   +3 more
core   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source