Results 51 to 60 of about 1,731,970 (301)

Construction and Immune Strategy Optimization of a Vaccine Strain for Influenza A (H5N8) Subtype

Viruses
Multiple subtypes of avian influenza virus (AIV), including H5N1, H5N6, and H5N8 viruses, are currently co-circulating in wild birds and poultry and causing sporadic human infections. Vaccine development is essential for pandemic preparedness.
Shuxia Zhang, Jing Tang, Liqi Liu, Hejiang Wei, Li Xin, Kang Xiao, Jinbo Xiao, Jie Dong, Zi Li, Hongyan Bai, Shuaixing Wang, Wenfei Zhu, Lei Yang, Shumei Zou, Dayan Wang   +14 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Health impacts of an extreme dust event: a case and risk assessment study on airborne bacteria in Beijing, China

Environmental Sciences Europe
Dust events are concerning due to their potential to cause environmental pollution and health issues by carrying numerous particles from various regions. However, the risks of airborne bacteria from dust have not yet been thoroughly investigated.
Yueyun Luo, Qiao Yao, Pei Ding, Min Hou, Fuchang Deng, Youbin Wang, Cheng Ding, Xia Li, Duochun Wang, Zongke Sun, Song Tang, Yixin Mao, Xiaoyuan Yao   +12 more
doaj   +1 more source

Preliminary assessment of the therapeutic potential of staphylococcal enterotoxin-like W via biological activity and TCR binding sites analysis

Virulence
Staphylococcal enterotoxin-like W (SElW) is a novel, widely prevalent enterotoxin-like protein that functions as a classical staphylococcal superantigen (SAg) and has been shown to exacerbate infections caused by the S.
Yuhua Yang, Xiaoyue Wei, Fanliang Meng, Yanan Gong, Yahui Guo, Lijin Long, Jiaming Fan, Yakun Zhao, Wanting Wang, Di Xiao, Lei Wang, Maojun Zhang, Dongliang Hu, Jianzhong Zhang, Xiaomei Yan   +14 more
doaj   +1 more source

Hydraulic system provides smooth control of large tracking and antenna drive systems at very low tracking rates [PDF]

, 1967
Hydraulic system provides smooth control of large tracking and antenna drive systems at very low tracking rates. This configuration modifies a series connection of the drive motors with compensating orifices to offset the effects of drain line loss ...
Parker, G. L.
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Dengue situation in Chinese mainland, 2023

BMC Public Health
Background Dengue fever outbreaks have occurred in Chinese mainland in recent years, especially in 2014 and 2019. In 2023, following the Corona Virus Disease 2019 pandemic, dengue fever has exhibited some new trends and characteristics.
Yujuan Yue, Xinchang Lun, Chunchun Zhao, Xiaobo Liu, Ning Zhao, Yuhong Guo, Xiuping Song, Liang Lu, Dongsheng Ren   +8 more
doaj   +1 more source

The cognitive demands of second order manual control: Applications of the event related brain potential [PDF]

, 1981
Three experiments are described in which tracking difficulty is varied in the presence of a covert tone discrimination task. Event related brain potentials (ERPs) elicited by the tones are employed as an index of the resource demands of tracking. The ERP
Donchin, E., Gill, R., Kramer, A., Ross, W., Wickens, C.   +4 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Characteristics of ESBL-positive Klebsiella pneumoniae isolated from paired children with and without diarrhea

Gut Pathogens
Background Klebsiella pneumoniae producing extended-spectrum β-lactamase (ESBL) colonizing and transmitting in the intestine, especially in children, have significant public health implications.
Yuan Zhang, Mengyu Wang, Zhenpeng Li, Yao Peng, Yuhan Yang, Xiao Liu, Zhe Li, Biao Kan, Mei Zeng, Xin Lu   +9 more
doaj   +1 more source