Results 61 to 70 of about 1,731,970 (301)

Mobile Formation Coordination and Tracking Control for Multiple Non-holonomic Vehicles

, 2019
This paper addresses forward motion control for trajectory tracking and mobile formation coordination for a group of non-holonomic vehicles on SE(2). Firstly, by constructing an intermediate attitude variable which involves vehicles' position information
Geng, Zhiyong,, Guo, Kexin,, Lund University., Peng, Xiuhui,, Sun, Zhiyong,   +4 more
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Transcriptome analysis of Kunming mice responses to the bite of Xenopsylla cheopis

Parasites & Vectors
Background Flea bites could trigger a series of complex molecular responses in the host. However, our understanding of the responses at the molecular level is still relatively limited.
Xinchang Lun, Yuan Shi, Yiguan Wang, Ning Zhao, Qiyong Liu, Fengxia Meng, Xiuping Song, Jun Wang, Liang Lu   +8 more
doaj   +1 more source

Morphological, lytic, and genetic characteristics of three Brucella phages isolated from Inner Mongolia Autonomous Region

Frontiers in Microbiology
This study comprehensively examined three Brucella phages (A1, NMY-1, and NMY-2) isolated from Inner Mongolia Autonomous Region. Electron microscopy classified them as short-tailed phages.
Yu Zhang, Yu Zhang, Dongri Piao, Qingqing Xu, Yu Fan, Hongyan Zhao, Kun Li, Guozhong Tian, Kuo Han, Hai Jiang   +9 more
doaj   +1 more source

Discrete Adaptive Second Order Sliding Mode Controller Design with Application to Automotive Control Systems with Model Uncertainties

, 2017
Sliding mode control (SMC) is a robust and computationally efficient solution for tracking control problems of highly nonlinear systems with a great deal of uncertainty.
Amini, Mohammad Reza, Hedrick, J. Karl, Pan, Selina, Shahbakhti, Mahdi   +3 more
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Optimization of the 5ʹ untranslated region of mRNA vaccines

Scientific Reports
To investigate the impact of different 5ʹ untranslated regions (UTRs) on mRNA vaccine translation efficiency, five dual-reporter gene expression plasmids with different 5ʹUTRs were constructed.
Qi Ma, Xiaoguang Zhang, Jing Yang, Hongxia Li, Yanzhe Hao, Xia Feng   +5 more
doaj   +1 more source

EBV gL-gH344-Ferritin Nanoparticle Vaccine Elicits Robust Immune Responses in Mice

Viruses
Considering the absence of a widely utilized EBV vaccine, we have developed an EBV gL-gH344-Ferritin nanoparticle vaccine utilizing ferritin as a carrier. The gL-gH344-Ferritin fusion gene was synthesized and inserted into the pET30a plasmid.
Chenyu Li, Yuxi Cao, Qi Ma, Jing Yang, Xiaoguang Zhang, Hongxia Li, Ke Xu, Tao Jiang, Shuying Li, Yanzhe Hao, Xia Feng   +10 more
doaj   +1 more source