Results 201 to 210 of about 250,878 (317)

Recent advances in the construction of humanized animal models and applications in translational medicine

Animal Models and Experimental Medicine, EarlyView.
Substantial advances have been achieved in the development of humanized mouse models, which have proven highly valuable in evaluating cancer immunotherapies and elucidating the mechanisms of infectious diseases. There is now a growing shift in research toward larger animal models—such as pigs—that offer greater physiological similarity to humans ...
Yanan Lyu, Yong‐Guang Yang, Zheng Hu
wiley   +1 more source

Non-Myopic Foveomacular Retinoschisis: Stellate Non-Hereditary Idiopathic Foveomacular Retinoschisis (SNIFR) and Central Anomalous Retinoschisis with Mid-Peripheral Traction (CARPET). [PDF]

Diagnostics (Basel)
Ruiz-Moreno JM, Zamorano M, Puertas M, Ruiz-Medrano J.   +3 more
europepmc   +1 more source

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

Advanced NanoBiomed Research, EarlyView.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham, Karthikeya S. V. Gottimukkala, Daniel D. Lane, Katrina Poljakov, Patricia Lipson, Mark R. Enstrom, Alessandro Rizzi, Aude G. Chapuis, Jennifer E. Adair   +8 more
wiley   +1 more source

Functional orthopedic treatment for mandibular asymmetry in a giant panda with amputation. [PDF]

Angle Orthod
Fan Q, Li J, Alkam E, You M, Luo L, Li B, Huang W, Chen X, Han X, Lai W, Long H.   +10 more
europepmc   +1 more source

Dental-floss traction-assisted endoscopic full-thickness resection of a gastrointestinal exophytic tumor: A case report. [PDF]

SAGE Open Med Case Rep
Chen X, Song X, Shi L, Guo H, Yu J.
europepmc   +1 more source

A simulation model to predict agricultural tractor-semi-trailer combination traction performance under different operating conditions. [PDF]

Sci Rep
Fouda T, Hegazy R, Alhamshary K.
europepmc   +1 more source

Thermal Calculations for Co‐Firing of Hydrogen/Ammonia and Coal in 660‐MW Coal‐Fired Boilers

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT To achieve a clean energy transition under the dual carbon goals, blending hydrogen/ammonia into pulverized coal boilers represents a key technological pathway. Different hydrogen/ammonia co‐firing ratios (5%–50%) are investigated for their impact on the thermodynamic characteristics of 660‐MW supercritical boiler at 100% and 20% boiler ...
Yaodong Da, Nana Hou, Weipeng Wang, Yongqiang Chang, Xin Liu, Feng Pan, Defu Che, Lei Deng   +7 more
wiley   +1 more source

Lateral versus supine positioning for proximal femoral nailing of unstable intertrochanteric fractures in geriatric patients: A prospective randomized comparative study. [PDF]

SICOT J
Ebied WF, Soubih HO, Haroun Y, Salem KA, Amin AA, Kotb AS.   +5 more
europepmc   +1 more source

Morphological and morphometric aspects of the equine aortic valve: New insights for comparative studies in mammals

The Anatomical Record, EarlyView.
Abstract New data on the equine aortic valve obtained using advanced techniques is especially important given the greater availability of animal models for translational research. Here we characterized the morphological and morphometric aspects of the equine aortic valve from 60 healthy hearts collected at equine abattoirs.
Vitor Pires Pereira, Victoria Brondani de Oliveira, Carlos Eduardo Seyfert, Luciano de Morais‐Pinto   +3 more
wiley   +1 more source

Mechanical cues regulate <i>in vitro</i> implantation of mouse embryos. [PDF]

Mater Today Bio
Liu Q, Chen K, Pan S, Zhang T, Wang Q, Zhu J, Zhang J, Jiang X, Jia H, Zheng S, Luo T.   +10 more
europepmc   +1 more source