Results 31 to 40 of about 299,357 (239)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

Research on traction load forecasting of electrified railway

open access: yes机车电传动, 2023
In order to ensure the power quality of traction power supply system and reduce the costs for purchasing electricity by traction substation, a probabilistic forecasting model of traction load based on sparse Gaussian process (SGP) is proposed.
LIU Fu, LIAO Qishu
doaj  

Evaluation of Property Difference between Traction Oil and Traction Grease

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2009
In this paper, the characteristics of traction grease are evaluated. The difference in film formation ability between traction oil and traction grease is focused on, and the state of film formation and the traction coefficient of traction oil and two ...
Masashi YAMANAKA   +3 more
doaj   +1 more source

Energy efficiency and integration of urban electrical transport systems: EVS and metro-trains of two real European lines [PDF]

open access: yes, 2019
Transport is a main source of pollutants in cities, where air quality is a major concern. New transport technologies, such as electric vehicles, and public transport modalities, such as urban railways, have arisen as solutions to this important problem ...
Cucala, Asunción P.   +3 more
core   +1 more source

Validation of a Genetic Risk Score Combined With Clinical Variables for Predicting Pulmonary Fibrosis in Early Rheumatoid Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective Pulmonary fibrosis (PF) is a severe extra‐articular manifestation of rheumatoid arthritis (RA). This study aimed to externally validate a genetic risk score (GRS) and a combined risk score (CRS) for predicting the risk of RA‐associated PF in an independent cohort of patients with early RA.
Mikael Brink   +3 more
wiley   +1 more source

Assessment of variability in traction interventions for patients with low back pain: a systematic review

open access: yesChiropractic & Manual Therapies, 2018
Background Previous systematic reviews have concluded that lumbar traction is not effective for patients with low back pain (LBP), yet many clinicians continue to assert its clinical effectiveness.
Muhammad Alrwaily   +2 more
doaj   +1 more source

Sizing and Energy Management of a Hybrid Locomotive Based on Flywheel and Accumulators [PDF]

open access: yes, 2009
The French National Railways Company (SNCF) is interested in the design of a hybrid locomotive based on various storage devices (accumulator, flywheel, and ultracapacitor) and fed by a diesel generator.
Akli, Cossi Rockys   +4 more
core   +2 more sources

Current Tracking Adaptive Control of Brushless DC Motors

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView.
In this paper, the current tracking for Brushless Direct Current motors is approached considering uncertainty in the parameters of the motor's model. An adaptive control scheme to compensate electrical parameters uncertainty is proposed without requiring any knowledge of the mechanical parameters.
Fernanda Ramos‐García   +3 more
wiley   +1 more source

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