Results 101 to 110 of about 70,699 (331)

Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots

open access: yesAdvanced Robotics Research, EarlyView.
This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou   +4 more
wiley   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

open access: yesAdvanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance   +17 more
wiley   +1 more source

Hyperviscous Diabetic Bone Marrow Niche Impairs BMSCs Osteogenesis via TRPV2‐Mediated Cytoskeletal‐Nuclear Mechanotransduction

open access: yesAdvanced Science, EarlyView.
Diabetic bone marrow exhibits pathological ECM hyperviscosity that activates TRPV2‐mediated Ca2⁺ influx, leading to perinuclear F‐actin disassembly, nuclear deformation, and chromatin condensation. This cytoskeletal‐nuclear decoupling suppresses osteogenic differentiation of BMSCs.
Yao Wen   +8 more
wiley   +1 more source

Complex driver movement mathematical model of the tractive rolling stock [PDF]

open access: yes, 2018
The paper developed a complex mathematical model of the rolling stock movement that takes into account the parallel operation of two real traction asynchronous engines of the first traction railway carriage and one equivalent engine of the second ...
Dmitrienko, Valery   +5 more
core  

A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells

open access: yesAdvanced Science, EarlyView.
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet   +5 more
wiley   +1 more source

Design of a novel traction converter for electric locomotive

open access: yesGong-kuang zidonghua, 2017
In view of problems of complex structure of main circuit and limited power and voltage existed in traditional traction system of AC-DC-AC electric locomotive, a traction converter for electric locomotive with single-phase AC input and three-phase AC ...
ZHANG Hongtao, NIU Xiaowei
doaj   +1 more source

In-wheel axial-flux SRM drive for light electric vehicles [PDF]

open access: yes, 2018
Revenues from global sales of light electric vehicles are expected to grow from $ 9.3 billion in 2017 to $ 23.9 billion in 2025. In order to boost this growth electric drives with better features and lower costs have to be developed.
Andrada Gascón, Pedro   +5 more
core  

An Opto‐Actuated Hydrogel for Cell Mechanoactuation and Real‐Time Force Monitoring

open access: yesAdvanced Science, EarlyView.
Researchers developed a mechanoactuated hydrogel interface where nanomachines exert forces on adhesion receptors and allow monitoring of traction force responses in real time. They demonstrate reversible talin recruitment, enhanced F‐actin polymerization, and a reduction in cell traction force when force is locally applied to focal adhesions of ...
Rinku Kumar   +6 more
wiley   +1 more source

HXD2F AC Drive Heavy-haul Freight Electric Locomotive

open access: yes机车电传动, 2019
The main technical parameters and characteristics of HXD2F AC drive heavy axle load freight electric locomotive were introduced. The main performances and characteristics of electric control system, traction system, braking system and mechanical system ...
Haiping WANG, Shiyong LYU, Hua LI
doaj  

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