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Traction forces in locomoting cells
Cell Motility, 1995AbstractA means of determining quantitative maps of the tractions exerted by locomoting cells on a substratum has been developed. This method is similar to the Harris silicone substratum assay [Harris et al., 1980: Science 208:177–179], but uses an improved non‐wrinkling film that deforms more predictably in response to traction forces. The method also
T, Oliver, M, Dembo, K, Jacobson
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Analysis of Traction Forces in a Precision Traction Drive
Journal of Tribology, 1986A theory for the shear stress between a rough elastic cylinder and a cylinder with a soft layer has been developed. The theory is based on a Fourier transform approach for the elasticity equations coupled with surface deflection equations for transient contacts.
J. W. Kannel, T. A. Dow
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Cell traction force and measurement methods
Biomechanics and Modeling in Mechanobiology, 2007Cell traction forces (CTFs) are crucial to many biological processes such as inflammation, wound healing, angiogenesis, and metastasis. CTFs are generated by actomyosin interactions and actin polymerization and regulated by intracellular proteins such as alpha-smooth muscle actin (alpha-SMA) and soluble factors such as transforming growth factor-beta ...
James H-C, Wang, Jeen-Shang, Lin
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Measurement of Minute Cellular Forces by Traction Force Microscopy
2022The ability of living cells to exert forces on their surrounding environment, such as the extracellular matrix (ECM) or neighboring cells, plays an important role in numerous biological processes. This chapter describes a simple protocol to measure forces exerted by living cells using traction force microscopy. This approach is based on the measurement
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Traction force microscopy in physics and biology
Soft Matter, 2014Adherent cells, crawling slugs, peeling paint, sessile liquid drops, bearings and many other living and non-living systems apply forces to solid substrates. Traction force microscopy (TFM) provides spatially-resolved measurements of interfacial forces through the quantification and analysis of the deformation of an elastic substrate.
Robert W, Style +8 more
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Compressed sensing traction force microscopy
Acta Biomaterialia, 2015Adherent cells exert traction forces on their substrate, and these forces play important roles in biological functions such as mechanosensing, cell differentiation and cancer invasion. The method of choice to assess these active forces is traction force microscopy (TFM).
Jonatan Bohr Brask +4 more
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Micropatterning tractional forces in living cells
Cell Motility, 2002AbstractHere we describe a method for quantifying traction in cells that are physically constrained within micron‐sized adhesive islands of defined shape and size on the surface of flexible polyacrylamide gels that contain fluorescent microbeads (0.2‐μm diameter).
Ning, Wang +3 more
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Measurement of cell traction forces with ImageJ
2015The quantification of cell traction forces requires three key steps: cell plating on a deformable substrate, measurement of substrate deformation, and the numerical estimation of the corresponding cell traction forces. The computing steps to measure gel deformation and estimate the force field have somehow limited the adoption of this method in cell ...
Martiel, Jean-Louis +7 more
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Orthopaedic traction device—an analysis of forces
Injury, 1984By using hanging weights as loads in traction treatment, one has to consider the transient forces created in the traction cord when the weights are displaced. These forces are transmitted to the patient who experiences them, at least in some circumstances, as pain or discomfort.
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Tire Traction and Force Transfer
2021The transfer of the forces and torques between the tire and the road surface is fundamental for all longitudinal and lateral motions of a vehicle. The physical effects of the force transfer depend on local properties at the contact patch. The amount of forces is a function of the frictional properties between the tire and the road surface.
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