Results 201 to 210 of about 576,681 (349)

Variational Thermomechanically Coupled Shape Memory Alloy Material Model and Optimization of Shape Memory Alloy Based Out‐of‐Plane Bistable Microactuator

open access: yesInternational Journal for Numerical Methods in Engineering, Volume 127, Issue 3, 15 February 2026.
ABSTRACT This work presents a fully thermomechanically coupled material model for shape memory alloys (SMAs), capable of predicting shape memory effect, superelasticity, stress and strain recovery, and martensite reorientation. Formulated within the Generalized Standard Material (GSM) framework, the model employs a rate potential, whose variations ...
Muhammad Babar Shamim   +2 more
wiley   +1 more source

A Novel Microfluidic System for 3D Epidermis and Full‐Thickness Skin Growth for Nanoparticle Safety Assessment

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 6, 9 February 2026.
This work presents a novel, dynamically perfused, configurable microfluidic system for epidermis‐only (E and full‐thickness skin (FT SoC) growth, emulating human skin structure and barrier function. Upon TiO2 nanoparticle exposure, the system reveals compromised barrier integrity, reduced metabolic activity, increased permeability, and chemokine‐driven
Samantha Costa   +7 more
wiley   +1 more source

Capillary Dynamics Analysis of Millimetric Tubes for Anti‐Slip Surfaces: A Phase‐Field Based Finite Element Approach and Experimental Validation

open access: yesAdvanced Theory and Simulations, Volume 9, Issue 2, February 2026.
Phase‐field method based numerical modelling of the capillary rise in millimeter‐sized tubes, aiming for anti‐slip applications. The experimental validation was performed through capillary assays in polyethylene oxide (PEO) bulk modified polydimethylsiloxane (PDMS) channels.
Shivam Sharma   +7 more
wiley   +1 more source

Promoting Autophagy Mitigates Stress‐Induced Remodeling in Patient iPSC‐CMs with the Phospholamban R9C Mutation

open access: yesAdvanced Science, Volume 13, Issue 7, 3 February 2026.
The Phospholamban (PLN) R9C mutation reduces SERCA2a binding, increasing calcium recycling and baseline contractility. However, the excess of free PLN promotes pentamer formation, limiting phosphorylation and blunting β‐adrenergic signaling. Under cardiac stress, enhanced functional demands overwhelm proteostasis in PLN R9C cells, leading to misfolded ...
Qi Yu   +10 more
wiley   +1 more source

Disrupting Lipid Raft Microdomains to Block Polyploid Giant Cancer Cell Budding and Enhance Radiotherapy Response

open access: yesAdvanced Science, Volume 13, Issue 9, 13 February 2026.
Radiation induces polyploid giant cancer cells (PGCCs) that regenerate tumors through virus‐like budding. This process depends on a SNCG–FLOT2–CHMP4B signaling axis functioning in lipid raft microdomains. Disrupting these domains using statins or anti‐PCSK9 antibodies blocks PGCC budding, suppresses tumor repopulation, and enhances radiotherapy ...
Zheng Deng   +20 more
wiley   +1 more source

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