Results 121 to 130 of about 220,761 (282)

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Biomimetic and Biophysical Approach to Profile Metastatic Cancer Cell Migration [PDF]

, 2018
Honors Research ScholarshipCancer metastasis is a complex process by which cells in a primary tumor acquire an aggressive phenotype, and travel to distant, secondary sites in the body.
Enders, Jacob
core  

Liver Stiffness Rises Early in MASLD and Drives Inflammation, Lipid Dysmetabolism, and Fibrosis via Piezo1–YAP Mechanotransduction

Advanced Science, EarlyView.
Progressive stiffening of the hepatic extracellular matrix and free fatty acid overload activate the mechanosensor Piezo1 in steatotic hepatocytes, inducing calcium influx and nuclear translocation of Yes‐associated protein. YAP‐dependent nuclear signaling further drives inflammatory and fibrotic gene programs, lipid metabolic reprogramming, and ...
Juan Ma, Ning Xie, Ziwei Wang, Xiru Liang, Yulong Han, Qiang Zhao, Ming Wang, Hongwei Lu, Wanyi Kou, William Alazawi, Jinhai Wang, Lu Li, Ning Liu, Na Liu, Haitao Shi, Feng Xu   +15 more
wiley   +1 more source

Study on Low-Frequency Oscillation in Train-Traction Network Coupling System Based on Impedance Model

机车电传动, 2017
The low-frequency oscillation phenomenon had been frequently occurred in China electrified railways, which caused the traction locked of the train and the protection tripped of power supply system as well as other accidents.
TAO Yan
doaj  

SDTC Neural Network Traction Control of an Electric Vehicle without Differential Gears

, 2007
International audienceThis paper proposes a Sensorless Direct Torque Control (SDTC) neural network traction control approach of an Electric vehicle (EV) without differential gears (electrical differential system).
Abdessemed, Rachid, Benbouzid, Mohamed, Diallo, Demba, Haddoun, Abdelhakim, Khoucha, Farid, Srairi, Kamel   +5 more
core   +1 more source

Beyond Transconductance: Cell‐Polymer Coupling Determines Fidelity in Action Potential Recording via Electrolyte‐Gated Polymer Transistors

Advanced Science, EarlyView.
High electrical performance alone does not guarantee efficient bioelectronic signal transduction. Despite excellent mixed ionic‐electronic conduction, recordings from cardiomyocytes reveal that p(g2T‐TT)‐based OECTs predominantly transduce field potential FP‐like signals due to weak cell‐polymer coupling.
Giulia Zoe Zemignani, Elena Mancinelli, Gabriele Tullii, Aleksandr Khudiakov, Cristiano Bortolotti, Shubham Tanwar, Peter J. Schwartz, Luca Sala, Maria Rosa Antognazza, Mario Caironi, Adrica Kyndiah   +10 more
wiley   +1 more source

Energetics of traction networks [PDF]

, 2017
Viktor Sychenko, Valeriy Kuznetsov, Dmitry Bosiy, Oleg Sablin   +3 more
openaire   +1 more source

Artificial Neural Network-Based Fault Identification for Grid-Connected Electric Traction Network

IEEE Access
Identifying the fault type and faulted phase prior to protection coordination and restoration of the remaining healthy part of the utility power grid in the presence of railway traction load is an important process to ensure power supply system reliability of the grid-connected traction network. An artificial neural network (ANN) based fault classifier
Shwe Myint, Prasenjit Dey, Phumin Kirawanich, Chaiyut Sumpavakup   +3 more
openaire   +2 more sources

Engineered Interpenetrating MXene Networks in Aramid Layered Films for Antioxidant and Broadband Electromagnetic Interference Shielding

Advanced Science, EarlyView.
This study introduces an innovative interpenetrating layered structure, comprising alternating aramid nanofiber (ANF) layers and MXene layers, fabricated through a directional freeze–thaw intercalation–gel‐film formation strategy. Unlike traditional homogeneous layered films, this unique layered structure features mutually embedded conductive and ...
Hongli Cheng, Gaojie Han, Congqi Liu, Yang Zhou, Yiming Wang, Bing Zhou, Yuezhan Feng, Chuntai Liu, Hao‐Bin Zhang, Changyu Shen   +9 more
wiley   +1 more source

Patient‐Derived 3D‐Bioprinted Intrahepatic Cholangiocarcinoma Models Recapitulate Tumor Autologous Traits and Predict Personalized Adjuvant Therapy

Advanced Science, EarlyView.
Leveraging 3D bioprinting, this study establishes patient‐derived in vitro models of intrahepatic cholangiocarcinoma. These models faithfully recapitulate the histopathology, molecular profiles, and genomic characteristics of the original patient tumors.
Yuce Lu, Liwei Du, Minghao Sun, Kai Zhang, Mingchang Pang, Shangze Jiang, Jiaxun Dong, Xiyue Liu, Bao Jin, Fu Xu, Hang Sun, Jiangang Zhang, Huiyu Yang, Xiaobo Yang, Xin Lu, Yiyao Xu, Haitao Zhao, Shunda Du, Xinting Sang, Yongchang Zheng, Lei Zhang, Xueshuai Wan, Huayu Yang, Yilei Mao   +23 more
wiley   +1 more source