Results 121 to 130 of about 18,604,702 (305)

scGEN: Leveraging an Adaptive Weighting Strategy for Challenging Cell Clustering in Single‐Cell RNA‐seq

open access: yesAdvanced Science, EarlyView.
scGEN combines attribute–structure encoding, adaptive hard‐sample weighting, and regularized zero‐inflated negative binomial loss to resolve ambiguous single‐cell states. In the developing human pituitary, refined annotations reveal Pre.Gonado cells at 7 weeks and previously obscured developmental communication networks.
Fang Huang   +16 more
wiley   +1 more source

Development of 18 t Eight-axle Passenger Electric Locomotive

open access: yes机车电传动, 2016
How to put "lightweight" concept into the every detail of equipment layout, ventilation system, electrical system,mechanical system, braking system, and wind system for locomotive development was introduced.
YUAN Zhiqiang, WU Xueliang
doaj  

Traction Drive Load Simulator

open access: yes
A stationary bench simulating the traction drive of electric transport vehicles in the traction and braking modes is employed in investigation of the drive operation with a hybrid energy storage system. The load simulator of the traction drive is made by
Zaļeskis, Genadijs   +3 more
core  

Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications

open access: yesAdvanced Science, EarlyView.
Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen   +11 more
wiley   +1 more source

PLXDC2 siRNA‐Mediated Intervention Attenuates Microglial Senescence Through cGAS‐STING Signaling

open access: yesAdvanced Science, EarlyView.
PLXDC2 was identified as a microglial target in Parkinson's disease through human and mouse single‐cell analyses. Ferritin‐armed biomimetic nanovesicles delivered PLXDC2 siRNA, deferoxamine, and CeO2 nanoparticles across the blood–brain barrier, reducing cGAS‐STING activation, iron burden, oxidative stress, and senescence in microglia, thereby ...
Heyue Lu   +13 more
wiley   +1 more source

Arthropod‐Inspired Miniature Modular Vibration Direct‐Drive Robot With Untethered Locomotion

open access: yesAdvanced Science, EarlyView.
This work presents an arthropod‐inspired untethered miniature modular vibration direct‐drive robot. By utilizing standardized driving units and nested locking interfaces, on‐demand reconfiguration into quadruped, hexapod, octopod, and circular morphologies is achieved.
Shijing Zhang   +4 more
wiley   +1 more source

Puget Sound Traction Electricity (1918)

open access: yes, 1918
Safer, cleaner and more economical than any other method. No matches necessary; turn on current - that's all. Full line of domestic heating appliances at this company's show rooms.
Puget Sound Traction, Light & Power Company
core  

Liquid‐Responsive Shape‐Memory Nanofiber‐Reinforced Scaffolds for Cartilage Repair

open access: yesAdvanced Science, EarlyView.
A liquid‐responsive shape‐memory, nanofiber‐reinforced QCG scaffold combines conformal defect filling, an aligned architecture that is structurally permissive for endogenous cell infiltration, and sustained KGN release. This integrated design enhances BMSC viability, migratory activity, and chondrogenic differentiation and promotes hyaline cartilage ...
Jiyang Zeng   +8 more
wiley   +1 more source

Permanent Magnet Synchronous Traction System for the Vehicles of Shenyang Metro Line 2

open access: yesKongzhi Yu Xinxi Jishu, 2012
It describes the main circuit of PMSM traction system for M car of the 20st vehicle for Shenyang Metro Line 2 as well as technical characteristic, parameters of PMSM, and compares the test results of motor loss and temperature-rise for PMSM traction ...
XIE Peijin   +3 more
doaj  

Brain Network Dynamics of Local and Global Predictive Processing in Aging

open access: yesAdvanced Science, EarlyView.
Separation of concurrent whole‐brain networks in source‐reconstructed magnetoencephalography (MEG) data suggests that healthy aging reorganizes, rather than uniformly attenuates, neural responses elicited from hierarchical auditory violations. Enhanced early sensory deviance processing alongside reduced higher‐order cognitive responses suggests a large‐
Mathias Houe Andersen   +9 more
wiley   +1 more source

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