Results 31 to 40 of about 8,238,807 (290)

Modeling the dispersal-reproduction trade-off in an expanding population [PDF]

, 2020
Trade-offs between dispersal and reproduction are known to be important drivers of population dynamics, but their direct influence on the spreading speed of a population is not well understood.
Maya L. Evenden, Mark A. Lewis, Nathan G. Marculis   +2 more
core   +1 more source

Determinan Leverage Optimal Di Bursa Efek Indonesia

Majalah Ilmiah Bijak, 2020
Research on capital structure, recently characterized by the use of dynamic capital structure. The use of dynamic capital structure basically wants to know the existence of optimal leverage as hypothesized by Trade-Off Theory and Speed off Adjustment ...
Purwanto Widodo, Juardi Juardi
doaj   +1 more source

Capital Structure Theories in US Corporate Divestitures: A Study on Spin-Off Firms

International Journal of Financial Studies
Some giant US conglomerates are now undergoing corporate spin-offs or are considering such spin-offs in the near future. Corporate spin-offs offer a unique opportunity to assess corporate capital structure decisions.
Xian Chen, Sanjib Guha, Tahsina Haque Simu   +2 more
doaj   +1 more source

Leverage, entrenched managers, and moderating effect of main shareholder’s influence [PDF]

Revista Contabilidade & Finanças
This study associated the leverage of Brazilian listed companies with their managers’ search for protection against the risk of main shareholder’s intervention.
Bruno José Canassa, Lucas Allan Diniz Schwarz, Maurício Ribeiro do Valle   +2 more
doaj   +1 more source

Optimal Capital Structure and Leverage Adjustment Speed of European Public and Private Firms

Economic and Business Review, 2020
In this research paper, the dynamic trade-off theory is tested by applying European public and private firms, since as much of the existing research remains in the US public firm context only.
Klemen Stegovec, Matjaž Črnigoj
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Teori Pecking Order dan Trade-Off dalam Analisis Struktur Modal di Bursa Efek Indonesia

Jurnal Siasat Bisnis, 2014
This study aims to test the pecking order theory and trade-off theory of capital structure in the analysis of the Indonesia Stock Exchange. Pecking order theory is represented by the variable profitability and growth, while the variables volatility of ...
D Agus Harjito
doaj   +4 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source