Results 61 to 70 of about 5,463,266 (359)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

TOOLS FOR MARKETING MANAGEMENT OF THE INNOVATION AND INVESTMENT ACTIVITY

open access: yesФінансово-кредитна діяльність: проблеми теорії та практики, 2022
The paper examines the processes of managing innovation and investment activity of enterprises with the complex use of marketing management tools.
Iryna Polishchuk   +4 more
doaj   +1 more source

From Trade-to-Trade in US Treasuries [PDF]

open access: yes, 2010
The aim of this paper is to model the trading intensity of the US Treasury bond market which has a unique expandable limit order book which distinguishes its structure from other asset markets.
Dungey, Mardi   +2 more
core  

Strategi Indonesia Dalam Mengatasi Hambatan Perdagangan Industri Tekstil Ke Turki [PDF]

open access: yes, 2023
This research will examine the strategies used by Indonesia in overcoming the problem of trade barriers in the textile industry to Turkey. 2014-2021 Indonesia has experienced a decrease in income.
Khofifah, Tasya
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

The impacts of intellectual capital of microfinance institutions on poverty alleviation

open access: yesHo Chi Minh City Open University Journal of Science - Economics and Business Administration
This study examines the impact of Intellectual Capital (IC) on poverty alleviation using a panel dataset of 3,114 Microfinance Institutions (MFIs) across 120 countries from 2009 - 2018.
Chi Tung Luong   +3 more
doaj   +1 more source

Transport accessibility as factor of excursion tourism development (case of Chernivtsi, Ukraine)

open access: yesČasopis Socìalʹno-Ekonomìčnoï Geografìï. Часопис соціально-економічної географії, 2016
In the course of scientific research found that for parameterization of complex socio-economic processes with the use of transport infrastructure in tourism advisable to use transport accessibility ratio (the ratio of current and potential routes) with ...
Roman Hyshchuk, Olexandra Pylypets'
doaj   +1 more source

Structure and Response in the World Trade Network

open access: yes, 2010
We examine how the structure of the world trade network has been shaped by globalization and recessions over the last 40 years. We show that by treating the world trade network as an evolving system, theory predicts the trade network is more sensitive to
A. Alesina   +5 more
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

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