Results 31 to 40 of about 178,028 (312)
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
A company’s market value: the methodology of its valuation and methods for its maximization [PDF]
International Economic Policy, 2007 This article investigates the creation and monitoring of the fundamental value of a company, the methods of its valuation, and capital market responses to changes of the fundamental value.
Olexandr Kravchenko
doaj
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Prospective of Transformation of Current Models of the Global Pharmaceutical Market [PDF]
International Economic Policy, 2012 This article thoroughly analyzes the current state of the global pharmaceutical market, defines the key factors for its development and outlines the promising areas of transformation of existing business models of top companies.
Yuriy Solodkovskyy, Olha Dovzhenko
doaj
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
Global Goals of Sustainable Development in Regional Policу of Ukraine [PDF]
International Economic Policy, 2017 The article presents the results of regional consultations concerning the regional priorities of sustainable development in Ukraine, initiated by the United Nations in 2016, and outlines the methodological suppositions and principles for expert system ...
Gromozdova Larysa, Gromozdov Volodymyr
doaj
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
The International Competitiveness of Nations: the Regional Aspect [PDF]
International Economic Policy, 2005 "This article examines the theoretical principles of the international competitiveness of nations as well as the main methodological principles of modern models of the international competitiveness of nations and regions.
Larysa Antoniuk
doaj
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley +1 more source
Integrative-index method of assessment of the countries’ financial globalization level [PDF]
International Economic Policy, 2009 The article considers the relevant problems of the complex evaluation of the countries’ financial globalization level. There were investigated methodological principles and assessment tools of both the economic globalization in general and its financial
Oleh Mozhovyi, Nataliia Stukalo
doaj