Results 51 to 60 of about 230,463 (298)

A Portrait of Trade in Value-Added over Four Decades [PDF]

open access: yesThe Review of Economics and Statistics, 2017
We combine data on trade, production, and input use to document changes in the value added content of trade between 1970 and 2009. The ratio of value-added to gross exports fell by roughly 10 percentage points worldwide. The ratio declined 20 percentage points in manufacturing, but rose in non-manufacturing sectors.
Johnson, Robert C. , Noguera, Guillermo
openaire   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Global Value Chains of COVID-19 Materials: A Weighted Directed Network Analysis

open access: yesMathematics, 2021
The COVID-19 pandemic caused a boom in demand for personal protective equipment, or so-called “COVID-19 goods”, around the world. We investigate three key sectoral global value chain networks, namely, “chemicals”, “rubber and plastics”, and “textiles ...
Georgios Angelidis   +5 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Environ-economic balance analysis in bilateral industrial trade: a comparison between Australia and China

open access: yesTechnological and Economic Development of Economy, 2022
Exchanges of products and services in bilateral industries may be accompanied by environmental and economic inequalities which lead to imbalanced situations in relation to environmental protection and economic development.
Qun Gao   +4 more
doaj   +1 more source

Differences between GTAP and TiVA databases and their Implications for Trade in Value-Added Indicators

open access: yes, 2022
Fragmentation of global production requires measurement of trade in value added, which accounts for the way slices of value embedded in goods or services are added at each step of increasingly international manufacturing processes within global supply ...
Ilaria Fusacchia
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Factories Europe, Asia, and North America as the main production centres in the 21st century

open access: yesInternational Entrepreneurship Review, 2020
Objective: The paper aims to present how the relations between countries in global value chains (GVC) changed at the beginning of the 21st century. Research Design & Methods: For this purpose, we propose two approaches. The first focuses on presenting
Aleksandra Nacewska-Twardowska
doaj   +1 more source

Are African exports that weak? A trade in value added approach [PDF]

open access: yesThe World Economy, 2020
AbstractAfrican countries are known to export less than any other group of countries in the world. Many studies have advanced that the main reason for this is the high level of transport costs due to the poor quality of transport infrastructures on the African continent.
openaire   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

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