Results 101 to 110 of about 137,827 (266)

Potent and Long‐Lasting Immunogenicity Generated by LNP‐mRNA gE Antigen Against Varicella Zoster Virus via an AI‐Assisted Pipeline

open access: yesAdvanced Science, EarlyView.
This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong   +6 more
wiley   +1 more source

A Quantum Framework for Protein Binding‐Site Structure Prediction on Utility‐Level Quantum Processors

open access: yesAdvanced Science, EarlyView.
This study presents a hybrid quantum‐classical framework for accurate prediction of protein structures on utility‐level quantum processors. We evaluate the practical application of the Variational Quantum Eigen‐solver (VQE) in protein structure prediction and demonstrate its superiority over state‐of‐the‐art deep learning methods in molecular docking ...
Yuqi Zhang   +10 more
wiley   +1 more source

Superelastic High‐Entropy Oxide Ceramic Aerogels for Thermal Superinsulation and Sealing at Extreme Conditions

open access: yesAdvanced Science, EarlyView.
A high‐entropy oxide ceramic of (Gd1/2Lu1/2)2(Ti1/3Zr1/3Hf1/3)2O7 is prepared through a molecular synthesis route of pyrolytic solid‐solution reactions. The architectured nanofiber aerogel manifests unprecedented thermomechanical properties, including superelastic compressibility of 98% from −196 to 1500 °C, and thermal superinsulation capacity (24.14 ...
Xiaoke Jiang   +9 more
wiley   +1 more source

A strategic framework to expand South Africa’s services trade

open access: hybrid, 2020
Susara J. Jansen van Rensburg   +4 more
openalex   +1 more source

All‐PEG‐Like Block Copolymers Self‐Assemble into Stealth Nanocarriers for Drug Delivery

open access: yesAdvanced Science, EarlyView.
Self‐assembling nanoparticles composed entirely of POEGMA are engineered by exploiting side‐chain–dependent amphiphilicity and tunable thermoresponsive behavior. These single‐material nanocarriers encapsulate diverse hydrophobic drugs with high efficiency, retain therapeutic activity, improve in vivo efficacy, and evade anti‐PEG antibodies.
Parul Sirohi   +15 more
wiley   +1 more source

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

open access: yesAdvanced Science, EarlyView.
Doehl et al. discovered an adaptive neuroimmune mechanism that induces itch in tick‐exposed guinea pigs, enabling rapid tick removal. This itch‐induced tick removal (IITR) is mediated by an adaptive cellular immune response and is independent of IgG, IgE, or TRPV1.
Johannes S. P. Doehl   +27 more
wiley   +1 more source

Significance and value of non-traded ecosystem services on farmland

open access: gold, 2015
Harpinder Sandhu   +5 more
openalex   +1 more source

Home - About - Disclaimer - Privacy